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Filtering by: Creator Huynh, Cuong Van Remove constraint Creator: Huynh, Cuong Van Subject DNA -- Structure Remove constraint Subject: DNA -- Structure

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  • The analysis and prediction of DNA structure

    Creator:
    Basham, Beth E.
    Abstract:
    As genome sequencing projects begin to come to completion, the challenge becomes one of determining how to understand the information contained within the DNA. DNA is a polymorphic macromolecule; the A- B- and Z-DNA conformations have been observed by a variety of physical techniques. The magnitude of the energetic differences...
    Resource Type:
    Dissertation
    Full Text:
    DNA solution structure and Dr. Kensal van Holde for his interest in this work. I also value the

  • The effect of cytosine methylation on DNA structure

    Creator:
    Vargason, Jeffrey M.
    Abstract:
    DNA methylation is common in prokaryotes and eukaryotes and has been implicated in various biological roles including gene silencing, X-chromosome inactivation, and genomic imprinting. 5-methylcytosine the "fifth base" of the genetic code comprises 1-3% of the human genome and is primarily found on cytosines within the context of the CpG...
    Resource Type:
    Dissertation
    Full Text:
    Acknowledgments We thank B. H. M. Mooers and the P. A. Karplus' laboratory for helpful discussion, and K. E. van