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  • Host kinases involved in DNA precursor biosynthesis during bacteriophage T4 infection

    Creator:
    Bernard, Mark Aguirre
    Abstract:
    Although the Escherichia coli host has almost all of the enzymes necessary to synthesize nucleotides needed for bacteriophage T4 DNA replication, phage genes expressed early in infection encode enzymes for de novo DNA precursor biosynthesis and salvage from degraded host DNA. Eight early enzymes and two host enzymes comprise the...
    Resource Type:
    Dissertation
    Full Text:
    : Host Kinases Involved in DNA Precursor Biosynthesis during Bacteriophage T4 Infection. Abstract

  • Organization of the T4 dNTP synthetase complex at DNA replication sites

    Creator:
    Kim, JuHyun
    Abstract:
    With respect to a multienzyme complex of deoxyribonucleoside triphosphate (dNTP) synthesis somehow juxtaposed with DNA replication sites, our laboratory has demonstrated the existence of a multienzyme complex in T4-infected E. coli, named the T4 dNTP synthetase complex, but the idea of direct linkage of dNTP synthesis to DNA replication and...
    Resource Type:
    Dissertation
    Full Text:
    of Bacteriophage T4 in E. coli ...................................17 2.2 Physical linkage among