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Filtering by: Subject Microsomes -- Effect of chemicals on Subject Developmental toxicology

In Utero Exposure to Arsenic and Mercury : Epigenome-Wide Associations and Newborn Health Outcomes

Creator:

Cardenas, Andres

Abstract:

Mercury and arsenic are known developmental toxicants and environmental exposures are ubiquitous worldwide from natural and anthropogenic sources. Prenatal exposure to both contaminants are independently associated with adverse perinatal health outcomes and latent disease risk that could be in part mediated by epigenetic reprogramming events. Fetal programming events involving DNA...

Resource Type:

Dissertation

Full Text:

methylation in different biological human tissues. Particularly, the effect of arsenic exposure on
Environmental estrogens and skeletal development disruption in the fathead minnow : A teleost model of vertebrate developmental toxicity

Creator:

Warner, Kara E.

Abstract:

Natural and synthetic estrogenic compounds detected in surface waters have been linked to endocrine signaling disruption in several species. Endogenous estrogen contributes to cartilage and bone deposition during development in vertebrates, and is susceptible to perturbation from xenoestrogens. The goals of this work were to develop a teleost model to...

Resource Type:

Dissertation