Index Catalog // ScholarsArchive@OSU

New product formulations and pharmacokinetics of acetaminophen

Creator:: Borin, Marie T.
Resource Type:: Dissertation
Full Text:: solutions: 1) 10% w/w starch in distilled water, 2) 10% w/w gelatin (175 bloom, Dyna Gel, Inc., Calumet

Dissolution and bioavailability of immediate and sustained release cold and cough dosage forms

Creator:: Hsu, Huey-yuh
Abstract:: A high-pressure liquid chromatography method based on reported literature was developed for the quantitative analysis of chlorpheniramine, pseudoephedrine, phenylpropanolamine and acetaminophen in dissolution fluids and urine. The effects of buffer, pH and different concentrations of organic solvent in the mobile phase on chromatographic separation are described in Chapter I. Dissolution...
Resource Type:: Masters Thesis
Full Text:: and E. L. Johnson, H. Chromatogr. Sci., 14,413 (1977). 4. C. Horvath, W. Melander, I. Mulnar, and P

Development and evaluation of an oral controlled release and a transdermal delivery system, for melatonin in human subjects

Creator:: Lee, Beom-jin
Resource Type:: Dissertation
Full Text:: System for Melatonin in Human Sublects. Abstract approved: James W. Ayres, Melatonin (MT

Development and in vivo testing of a gastric retention device (GRD) in dogs

Creator:: Kapsi, Shivakumar G.
Abstract:: This thesis describes 1) development of a gastric retention device (GRD) to increase gastric retention time of certain drugs, 2) product formulations of an immediate release itraconazole and controlled-release ketoprofen. GRD was fabricated from crosslinked carbohydrate polymers. Rate and extent of hydration of the film in water and in simulated...
Resource Type:: Dissertation
Full Text:: received from my Prof. James W. Ayres during my graduate studies. I consider myself privileged to have

A novel self-sealing chewable sustained release tablet of acetaminophen ; Development and evaluation of novel itraconazole oral formulations ; A novel zero order release matrix tablet

Creator:: Rakkanka, Vipaporn
Abstract:: This thesis describes evaluation of a novel self-sealing chewable sustained release tablet that can maintain controlled release of drug regardless of compaction, crushing, or chewing. The new formulation contains polyethylene oxide which produces a sealant effect for cracks produced in the polymer coating during compaction. Dissolution studies were conducted and...
Resource Type:: Dissertation
Full Text:: Oral Formulations, (3) A Novel Zero Order Release Matrix Tablet. Abstract approved James W This

In vitro and in vivo testing of a gastric retention device : development and evaluation of a new colonic delivery system

Creator:: Ahmed, Iman Saad
Abstract:: This thesis describes evaluation of a gastric retention device (GRD) developed at Oregon State University. The device was originally fabricated from Xanthan gum and Locust bean gum. A modified gastric retention device containing other additives was developed and investigated in this work. The modified device was evaluated in vitro for...
Resource Type:: Dissertation
Full Text:: W. Ayres 4 ABSTRACT A gastric retention device (GRD) fabricated from cross-linked carbohydrate

Development of Hot-melt Pan-coating, Application to Sustained-release Capsules and Tamper Resistant-coating. 2) Formulation of Verapamil HCl and Diltiazem HCl Semisolid Matrix Capsules. 3) Novel Sustained Release Tablet of Glipizide: Compression of Coated Drug Beads, Formulation, Dissolution, and Convolution. 4) Verapamil Sustained Release: New Formulation and Convolution

Creator:: Nguyen, Chien Ngoc
Abstract:: Hot-melt pan-coating, which is a novel coating method and takes 2-3 hours for 300 mg coating weight gain per capsule and tamper-resistant coating, which takes 30 minutes, is much faster than tedious sugar coating and allows greater coating weight gains in shorter times than spray-melt coating. Although hot-melt pan coating...
Resource Type:: Dissertation
Full Text:: approved: James W. Ayres J. Mark Christensen Hot-melt pan-coating, which is a novel

Preparing sustained release dosage forms of nifedipine by hot-melt coating method

Creator:: Le, Hang Thi
Abstract:: A nifedipine sustained release dosage form was prepared by using hot-melt batch coating. Substrates are sugar beads, mesh size 30-35. Stearic acid, Acid Triglyceride, and carnauba wax were coating agents used to make single layer coated beads and multiple layer coated beads containing nifedipine. Dissolution of nifedipine from the beads...
Resource Type:: Masters Thesis
Full Text:: Nifedipine by Hot-melt Coating Method Abstract J. Mark Christensen (I James W Ayres A nifedipine

Hydrocortisone permeation study using a synthetic membrane, mouse skin and an epiderm cultured skin, Preparation of orally disintegrating tablets of melatonin and acetaminophen, Pharmacokinetics of terbinafine in penguins

Creator:: Le, Hang Thi
Abstract:: The first project of this thesis is an in vitro study. This study was performed with 8 hydrocortisone topical products on the market for the purpose of comparing one Tec Lab product, a Corticool gel, to the other seven common products on the market. The permeation of these products was...
Resource Type:: Dissertation
Full Text:: Christensen James W. Ayres The first project of this thesis is an in vitro study. This

ScholarsArchive@OSU

New product formulations and pharmacokinetics of acetaminophen

Dissolution and bioavailability of immediate and sustained release cold and cough dosage forms

Development and evaluation of an oral controlled release and a transdermal delivery system, for melatonin in human subjects

Development and in vivo testing of a gastric retention device (GRD) in dogs

A novel self-sealing chewable sustained release tablet of acetaminophen ; Development and evaluation of novel itraconazole oral formulations ; A novel zero order release matrix tablet

In vitro and in vivo testing of a gastric retention device : development and evaluation of a new colonic delivery system

Preparing sustained release dosage forms of nifedipine by hot-melt coating method

Hydrocortisone permeation study using a synthetic membrane, mouse skin and an epiderm cultured skin, Preparation of orally disintegrating tablets of melatonin and acetaminophen, Pharmacokinetics of terbinafine in penguins

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