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Filtering by: Advisor Frederick, W. James Remove constraint Advisor: Frederick, W. James Subject Dyphylline Remove constraint Subject: Dyphylline

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Bioavailability and pharmacokinetics of dyphylline and theophylline in rabbits

Creator:

Mayo, Charles Edward

Abstract:

The bioavailability and pharmacokinetics of theophylline in rabbits were determined following both oral and intravenous administration of the drug. Serum theophylline concentrations were determined using high pressure liquid chromatography. Pharmacokinetic parameters were determined and verified by computer analysis. The overall mean Beta disposition constant was 0.089 hr⁻¹ which corresponds to...

Resource Type:

Masters Thesis

Full Text:

DYPHYLLINE AND THEOPHYLLINE IN RABBITS Abstract approved: Redacted for Privacy Dr. James W. Ayres V Part
Comparative pharmacokinetic studies of dyphylline and some dyphylline prodrugs

Creator:

Huang, Hua-pin

Abstract:

Dyphylline is an analog of theophylline and the latter is the most popular member of the methylxanthine family in use for the treatment of asthma. Although dyphylline is devoid of some problems associated with theophylline, a reported short half-life has made it's clinical usefulness limited. To avoid this problem a...

Resource Type:

Masters Thesis

Full Text:

....- v,....- ,-...- Dr. James W. Ayre i Dyphylline is an analog of theophylline and the latter is the
Pharmacokinetic modeling of theophylline and dyphylline and pharmacodynamics of ibuprofen input rate on antipyresis

Creator:

Stevens, Ruth E.

Abstract:

Pharmacokinetic parameters for theophylline and dyphylline were evaluated in horse cerebrospinal fluid (csf) and plasma. Pharmacokinetic parameters did not differ significantly (p > 0.05) at the same dose for either drug when administered alone or concomitantly. Theophylline and dyphylline penetrate horse csf to produce approximately 1/2 the concentrations found in...

Resource Type:

Dissertation

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addition, I would like to thank: Dr. James W. Ayres, my major advisor, for his guidance, valuable advice
Prolonged duration of action of dyphylline through prodrugs

Creator:

Panomvana, Duangchit

Resource Type:

Dissertation

Full Text:

. Redacted for privacyAbstract approved: ?'Dr. James W. Ayres A series of four diesJrs and four monoesters

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Academic Affiliation

School of Pharmacy2
College of Pharmacy1
Pharmaceutical Science1

Advisor

Ayres, James W.4

Commencement Year

Commencement Year range begin – Commencement Year range end

Current results range from 1977 to 1993

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Creator

Huang, Hua Pin1
Mayo, Charles Edward1
Panomvana, Duangchit1
Stevens, Ruth E.1

Date

Date range begin – Date range end

Current results range from 1976 to 1992

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Decade

1990-19991
1980-19891
1970-19792

Degree Field

Pharmacy3
Pharmaceutical Science1

Degree Level

Doctoral2
Master's2

Degree Name

Doctor of Philosophy (Ph.D.)2
Master of Science (M.S.)2

Language

English [eng]4

Non-Academic Affiliation

Oregon State University. Graduate School4

Peer Reviewed

No4

Resource Type

Dissertation2
Masters Thesis2

Rights Statement

Copyright Not Evaluated4

Subject

Dyphylline[remove]4
Anti-inflammatory agents1
Ibuprofen1
Theophylline1

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