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Filtering by: Subject Hypotensive agents -- Controlled release Subject Hypotensive agents -- Pharmacokinetics

Development and in vivo testing of novel hydrochlorothiazide gastric retention formulations in healthy volunteers and stage I hypertensive patients

Creator:

Farid, Samar Farghali

Abstract:

This thesis describes in vitro and in vivo evaluation of a gastric retention formulation (GRF) developed at Oregon State University. The formulation was prepared from xanthan gum and locust bean gum as gelling agents and other formulation ingredients were added, then it was originally vacuum oven dried. The effect of...

Resource Type:

Dissertation

Full Text:

controlled release drug delivery systems. Oral dosage forms pass through the small intestine, the principal