Index Catalog // ScholarsArchive@OSU

Start Over

Filtering by: Subject Ionizing radiation -- Physiological effect Subject Genetic recombination

Hypermutagenic induction of mitotic recombination by ionizing radiation in Mlhl null mouse cells

Creator:

Wang, Qi

Abstract:

Mitotic recombination is a common autosomal mutation in mammalian cells involving crossover events between homologous chromosomes. This process can convert a cell with a heterozygous deficiency to one with a homozygous deficiency, and thus often represents the second step in tumor suppressor gene inactivation. In this study I examined the...

Resource Type:

Masters Thesis