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Filtering by: Creator Pinard, Zachary J. Remove constraint Creator: Pinard, Zachary J. Subject Lyngbya Remove constraint Subject: Lyngbya

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  • Biologically active cyclic depsipeptides from marine cyanobacteria

    Creator:
    Medina, Rebecca A.
    Abstract:
    This thesis describes the chemical investigation of marine cyanobacteria collected in Madagascar and Panama with an emphasis on the isolation and structure elucidation of medicinally relevant secondary metabolites. A collection of the marine cyanobacterium Lyngbya majuscula from the Radames Islands, Madagascar yielded two new cyclic depsipeptides, radamamides A and B,...
    Resource Type:
    Dissertation
    Full Text:
    , 689-696. (7) Newman, D. J.; Cragg, G. M.; Snader, K. M. Nat. Prod. Rep. 2000, 17, 215- 234. (8

  • Cloning and biochemical characterization of the hectochlorin biosynthetic gene cluster from the marine cyanobacterium Lyngbya majuscula

    Creator:
    Ramaswamy, Aishwarya V.
    Abstract:
    Cyanobacteria are rich in biologically active secondary metabolites, many of which have potential application as anticancer or antimicrobial drugs or as useful probes in cell biology studies. A Jamaican isolate of the marine cyanobacterium, Lyngbya majuscula was the source of a novel antifungal and cytotoxic secondary metabolite, hectochlorin. The structure...
    Resource Type:
    Dissertation
    Full Text:
    - +H3N ..7.__&:)L..ir0 N FL j 0 R £ R FMN R Figure 1.7: Reactions catalyzed by NRPS tailoring domains

  • Natural products studies of the marine cyanobacterium Lyngbya majuscula

    Creator:
    Sitachitta, Namthip
    Abstract:
    The marine cyanobacterium Lyngbya majuscula has proven to be extraordinarily rich in bioactive secondary metabolites. This dissertation describes the chemistry of L. majuscula collected from Grenada, Fiji and Papua New Guinea, and the biosyntheses of two L. majuscula metabolites, curacin A and barbamide. The chemical studies with a Grenada collection...
    Resource Type:
    Dissertation
    Full Text:
    DEPT 1H mult (J =Hz) 13C DEPT 1H mult (J =Hz) 1 169.63 c 170.51 c 2 34.02 CH2 2.49 t (7.3) 34.14 CHz