The purpose of this research was to determine if a basic protein
was associated with the DNA of Bacillus subtilis W168, and to determine
if there was a difference in the amount and type of protein
associated with the DNA at different times during the growth cycle
of the organism....
I have investigated nucleoprotein organization in
chromatin of the yeast, Saccharomyces cerevisiae. My
approach has been to prepare insoluble, minimally per
turbed chromatin from a mitochondrial DNA-free strain of
yeast, using a number of new techniques, and then digest
this substrate with micrococcal nuclease. The soluble
products are electrophoresed on...