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Filtering by: Creator Simonich, Staci L. Massey Remove constraint Creator: Simonich, Staci L. Massey Subject Polycyclic aromatic hydrocarbons -- Carcinogenicity Remove constraint Subject: Polycyclic aromatic hydrocarbons -- Carcinogenicity

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  • Toxicogenomic Biomarkers Associated with PAH Carcinogenic Potential in a 3D in Vitro Bronchial Epithelial Model

    Creator:
    Chang, Yvonne
    Abstract:
    The environmental health science community recognizes polycyclic aromatic hydrocarbons (PAHs) as a re-emerging class of environmental pollutants due to their persistence and prominence in mixtures of concern. Due to their widespread distribution in the environment, exposure to PAHs often occur as complex chemical mixtures. Exposures are linked to numerous adverse...
    Resource Type:
    Dissertation
    Full Text:
    . Staci Simonich, Dr. David Williams, Dr. Barbara Taylor, and Dr. Molly Megraw for their contributions

  • Human Exposure to PAHs in Air, Water, and Crayfish

    Creator:
    Paulik, L. Blair
    Abstract:
    There are many links between exposure to environmental pollution and risks to human health. While advances in the fields of toxicology, exposure science, and environmental chemistry have shown light on many of these links, many more research challenges remain. One major challenge is how to accurately characterize the toxicity of...
    Resource Type:
    Dissertation
    Full Text:
    . Thank you to Dave Stone, Bill Stubblefield, Staci Simonich, Molly Kile, Anna Harding, and Perry Hystad

  • Toxicity and Mutagenicity of Polycyclic Aromatic Hydrocarbons in Contaminated Soils using Mammalian In Vitro Assay

    Creator:
    Luker, George W.
    Abstract:
    There exists a growing need to establish a better in vitro model for evaluating PAH toxicity and carcinogenicity and to improve assessments of risk to human health, especially to the complex mixtures that exist in the environment. Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental contaminants due to the incomplete combustion...
    Resource Type:
    Undergraduate Thesis
    Full Text:
    classification of the soil extracts obtained from the Puget Sound Superfund site was performed by the Simonich