Index Catalog // ScholarsArchive@OSU

Start Over

Filtering by: Subject Tetrachlorodibenzodioxin -- Toxicology Subject Pyruvate carboxylase

Characterization of pyruvate carboxylase responses to 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure in C57BL/6J male Ah[superscript d/d] mice

Creator:

Ryu, Byung-Woo

Resource Type:

Dissertation

Full Text:

THE THESIS OF Byung-Woo Ryu for the degree of Doctor of Philosophy in Toxicology presented on
Characterization of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induced modification of hepatic pyruvate carboxylase gene expression in C57BL/6J male mice

Creator:

Sparrow, Barney R.

Abstract:

The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure on hepatic pyruvate carboxylase (PC) gene expression were investigated in C57BL/6J Ah[superscipt b/b male mice. A dose-dependent reduction of PC levels and activity occurred in animals given a single intraperitoneal dose of TCDD in a corn oil carrier. The dose ranged from 1 to...

Resource Type:

Dissertation

Full Text:

OF THE THESIS OF Barney R. Sparrow for the degree of Doctor of Philosophy in Toxicology presented