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Filtering by: Creator Ortíz-Lozano, Leonardo D. Remove constraint Creator: Ortíz-Lozano, Leonardo D. Subject Transcription factors Remove constraint Subject: Transcription factors

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  • Modulation of metabolic syndrome by soy isoflavones : in-vitro and in-vivo models

    Creator:
    Luo, Ting
    Abstract:
    Metabolic syndrome is a problem affecting people around the world. In a number of studies, soy intake has been documented to possess antidiabetic and anticardiovascular effect. My project is focused on the impact of the intake of compounds found within soy, the isoflavones, their impact on metabolic syndrome symptoms, and...
    Resource Type:
    Dissertation
    Full Text:
    daidzein (WD+D) for 10 weeks. Surprisingly, intake of WD+G and WD+D significantly decreased food intake

  • Gene regulatory networks during muscle development

    Creator:
    Eng, Diana G.
    Abstract:
    Congenital myopathies are caused by heritable mutations in particular genes. Genes mutated in congenital muscular dystrophies often encode cytoskeletal proteins, which contribute to the shape and movement of cells. We would like to know how such molecular defects lead to the muscle weakness in patients. It is therefore important to...
    Resource Type:
    Dissertation
    Full Text:
    (Pitx2a, b, c, d) and three in mice (Pitx2a, b, c), all sharing the same C-terminal region and homeobox

  • Roles of homeodomain transcription factors during organogenesis

    Creator:
    Xu, Jun
    Abstract:
    The spatial and temporal patterning of sequence specific transcription factors (SSTFs) contributes to cell type specification and organ formation during embryogenesis. Homeodomain transcription factors are evolutionally conserved among invertebrate and vertebrate animals. They are responsible for body segmentation and organogenesis. Lbx1 and Pitx2 both are homeodomain transcription factors contributing to...
    Resource Type:
    Dissertation
    Full Text:
    FIGURES (CONTINUED) Figure 4-4. RNA Expression Pattern of A Cluster and D Cluster Hox Genes

  • Gene networks during cardiogenesis and skeletal myogenesis

    Creator:
    Ma, Hsiao-Yen
    Abstract:
    Organismal development requires a precisely orchestrated transcriptional program to correctly deploy genetic information into the genome. This process requires sophisticated gene regulatory networks at multiple spatial and temporal levels from early embryonic development to adult physiological conditions. Molecular differences that define cell types are set up during the pattern formation...
    Resource Type:
    Dissertation
    Full Text:
    states of embryonic and adult muscle cells (Shih et al., 2007c) and acts upstream of Pax3/Pax7 (Lozano

  • The role of the transcriptional regulatory protein BCL11B in dental and craniofacial development

    Creator:
    Kyrylkova, Kateryna
    Abstract:
    BCL11B is a transcriptional regulatory protein that plays essential roles during mouse embryonic development. BCL11B is expressed and functions in the immune and nervous systems as well as within ectodermal organs. Multiple studies have characterized the roles of BCL11B in T cells, brain, and skin. However, very little is known...
    Resource Type:
    Dissertation
    Full Text:
    basal ganglia disorders. Trends Neurosci 12, 366-75. Albu, D. I., Feng, D., Bhattacharya, D., Jenkins

  • Role of Transcriptional Factor COUP-TF-interacting Proteins in Skin Permeability Barrier Development, and in Skin Carcinogenesis, and Role of Lipids in Atopic Dermatitis

    Creator:
    Li, Shan
    Abstract:
    Mammalian skin is the largest organ of the body and serves as a barrier to protect the body against chemical, mechanical and pathogenic insults as well as water loss. The epidermis is formed from the primitive ectoderm into a multilayered stratified epithelium, consisting of basal, spinous, granular and outermost cornified...
    Resource Type:
    Dissertation