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Filtering by: Committee Member Braunworth, Bill Subject Viral genetics

Genomic characterization of a novel leporid Herpes simplex virus

Creator:

Babra, Bobby A.

Abstract:

The viral family Herpesviridae consists of large double stranded DNA viruses including eight species that infect humans with varying pathology from benign rashes to cancerous cell transformation. From three subfamilies, alpha-, beta- and gammaherpes, the alphaherpes contains the genera iltovirus, mardivirus, varicellovirus and simplex, two of which, the human simplex...

Resource Type:

Dissertation
Translation of dengue virus RNA : influence of the untranslated regions on 5´-cap dependent translation and ribosome scanning

Creator:

Chiu, Wei-Wei

Abstract:

In this thesis, I studied the translation of dengue virus RNA using a luciferase reporter gene system in Vero cells. The dengue reporter mRNA construct, which harbors 5´-terminal viral nts and 3´-terminal nts, could be translated efficiently compared to an alpha globin reporter construct. The 5´-cap structure and 3´-untranslated region...

Resource Type:

Dissertation

Full Text:

to Dr. George Rohrmann, Dr. Valerian Dolja, Dr. Walt Ream, Dr. Bill Braunworth and Dr. Rhian Cope