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Filtering by: DOI 10.1289/ehp.1205925 Subject Zebra danios as laboratory animals

Embryonic and Larval Zebrafish Bioassays for Biomedical Research : The Larval Photomotor Response Screening Assay and Phenotype

Creator:

Fisher, Joseph A.

Abstract:

Laboratories around the world are using the zebrafish model for biomedical research and conducting investigations using morphological, physiological, behavioral, and genomic endpoints. All assays provide information, but physiological and behavioral endpoints or phenotypes are a fast way to understand how an animal is responding to its environment. We investigate the...

Resource Type:

Dissertation

Full Text:

Chemicals: A Tox21 Update. Environ. Health Perspect. doi:10.1289/ehp.1205784 17 2 Literature Review
Developing rapid in vivo assays to investigate structure response relationships

Creator:

Truong, Lisa

Abstract:

Incorporation of nanoparticles (NPs) into consumer products is on the rise and human exposure to NPs is unavoidable. Currently, there is insufficient data to assess the safety of nanoparticles. I conducted a series of five studies using the zebrafish model to determine which NP components (i.e., core material or surface...

Resource Type:

Dissertation