Knowledge workers are struggling in the information flood. There is a growing interest in intelligent desktop environments that help knowledge workers organize their daily life. Intelligent desktop environments allow the desktop user to define a set of “activities” that characterize the user’s desktop work. These environments then attempt to identify...
How can an agent generalize its knowledge to new circumstances? To learn
effectively an agent acting in a sequential decision problem must make intelligent action selection choices based on its available knowledge. This dissertation focuses on Bayesian methods of representing learned knowledge and develops novel algorithms that exploit the represented...
We have recently reported that cell-penetrating peptides (CPPs) and novel chimeric peptides containing CPP (referred as
B peptide) and muscle-targeting peptide (referred as MSP) motifs significantly improve the systemic exon-skipping activity
of morpholino phosphorodiamidate oligomers (PMOs) in dystrophin-deficient mdx mice. In the present study, the general
mechanistic significance of the...
This dissertation incorporates coalition formation and probabilistic planning towards a domain-independent automated planning solution scalable to multiple heterogeneous robots in complex domains. The first research direction investigates the effectiveness of Task Fusion and introduces heuristics that improve task allocation and result in better quality plans, while requiring lower computational cost...
Multiagent approaches are well suited to designing autonomous solutions for systems that feature complex interactions between many individuals such as in autonomous traffic systems and multi-robot exploration systems. However, creating autonomous agents that function effectively in these systems is a challenging task. In these complex environments, agents need informative reward...
Autonomous multiagent teams can be used in complex exploration tasks to both expedite the exploration and improve the efficiency. However, use of multiagent systems presents additional challenges. Specifically, in domains where the agents' actions are tightly coupled, coordinating multiple agents to achieve cooperative behavior at the group level is difficult....
In 2017, the cost of congestion in the United States was around 305 billion dollars, and city-dwellers, on average, lost 1400 dollars while sitting 42 hours in traffic jams. Aiming for better mobility and more efficient utilization of the transportation network, emerging connected and autonomous vehicle (CAV) technologies and their...
The functioning of marine habitats needs to be understood in the context of the ecological relationships and associations between organisms and the physical and biogenic environment they inhabit. Thus, it becomes important to explore and define habitat features which contribute to these relationships and which are important in the life...
Markov Decision Processes (MDPs) are the de-facto formalism for studying sequential decision making problems with uncertainty, ranging from classical problems such as inventory control and path planning, to more complex problems such as reservoir control under rainfall uncertainty and emergency response optimization for fire and medical emergencies. Most prior research...
Building intelligent computer assistants has been a long-cherished goal of AI. Many intelligent assistant systems were built and fine-tuned to specific application domains. In this work, we develop a general model of assistance that combines three powerful ideas: decision theory, hierarchical task models and probabilistic relational languages. We use the...