Alzheimer’s Disease (AD) is an abnormal part of aging that mainly affects those over the age of 65. The current therapies are only FDA approved for mild to moderate AD symptoms. Cannabidiol (CBD) is a non-intoxicating constituent of Cannabis sativa that has been shown to have beneficial effects on cancer,...
Vietnam is considered one of the most climate change-vulnerable countries due to its high dependence on agriculture and its coastal location. Increased atmospheric temperatures caused by climate change also significantly threaten one of Vietnam's most important cash crops, robusta coffee (Coffea canephora). Suitable cultivation sites of robusta, which comprises 97%...
River ecosystems throughout the arid southwestern U.S. are imperiled. Water management infrastructure, climate change, unsustainable water use, and political conflict harm the region's aquatic and riparian ecosystems. This case study surveys one such desert river, an endemic fish species, and conservation efforts in southwestern Utah. The analysis focuses on the...
Iterative algorithms are simple yet efficient in solving large-scale optimization problems in practice. With a surge in the amount of data in past decades, these methods have become increasingly important in many application areas including matrix/tensor recovery, deep learning, data mining, and reinforcement learning. To optimize or improve iterative algorithms,...
Pesticides benefit agriculture by increasing crop yield, quality, and security. However, pesticides may inadvertently harm bees, which are valuable as pollinators. Thus, candidate pesticides in development pipelines must be assessed for toxicity to bees.
Leveraging a data set of 382 molecules with toxicity labels from honey bee exposure experiments, we...
Recent shifts from clearcutting to partial retention harvesting on many ownerships and the importance of microclimate dynamics on biotic responses to regional climate highlight the need to understand how microclimate conditions in forest understories differ across gradients of partial overstories. This study compares below-canopy near-surface temperatures at 2cm above ground...
Balancing selection is one of the mechanisms which has been proposed to explain the maintenance of genetic diversity in species across generations. For species with large populations and complex life histories, however, heterogeneous selection pressures may create a scenario in which the net effects of selection are balanced across developmental...
The climate of the Pacific Northwest is in flux, and existing forest ecosystems are stressed and poised to shift in fundamental ways, with or without human intervention. This dissertation probes the nature of forest responses to environmental change through investigations of morphology and genetics of three species of alder co-occurring...
Ph.D. candidate Qi Wei's thesis consists of two projects: Chemotherapy Project: a study based on the research paper "Predicting chemotherapy response of various cancer types using a variational auto-encoder approach" submitted to the bioRxiv preprint archive and accepted by the BMC bioinformatics; and Wound Monitor Project: implementing and assessing analytics...
Dietary nitrate (NO3-), consumed primarily from leafy green and root vegetables, lowers blood pressure, improves vascular function and aerobic exercise performance. This performance-enhancing effect of nitrate supplementation is largely attributed to the increased bioavailability of the signaling molecule, nitric oxide (NO). Nitric oxide is a ubiquitous free radical signaling molecule...