The focus of this thesis is to design, characterize, and apply novel computational methods and molecular systems to interrogate heterogeneous human gut microbiome-related phenomena. In Chapter 2, I design, implement, and characterize a method for embedding co-occurrence patterns derived from massive 16s amplicon datasets. I use this method to 1....
This dissertation delves into understanding, characterizing, and addressing dataset shift in deep learning, a pervasive issue for deployed machine learning systems. Integral aspects of the problem are examined: We start with the use of counterfactual explanations in order to characterize the behavior of deep reinforcement learning agents in visual input...
Many people around the world suffer from a mental illness, and too few receive the help they need. Mental illness is especially prevalent among the homeless. Homelessness is represented in all ages, ethnicities, and genders, and is especially represented among first world countries such as the United States and Spain....
Advances in mobile autonomous vehicles for oceanographic sensing provide new opportunities for passive acoustic monitoring of marine mammals. Acoustically equipped mobile autonomous platforms, including gliders, deep-water profiling floats, and drifting surface buoys can survey for a variety of marine mammal species over intermediate spatiotemporal scales. Additionally, such mobile platforms may...
This dissertation incorporates coalition formation and probabilistic planning towards a domain-independent automated planning solution scalable to multiple heterogeneous robots in complex domains. The first research direction investigates the effectiveness of Task Fusion and introduces heuristics that improve task allocation and result in better quality plans, while requiring lower computational cost...
The 134-year old Frantz-Dunn House in Hoskins, Oregon is an intact, well-preserved example of rural Gothic architecture in the Willamette Valley. The old farmstead sits on a former Civil War Fort site and represents a link in the history of the region to the larger patterns of expansion in America...
The fact that 80 percent of Mexican forestlands are under common ownership impacts the competitiveness of the forest products industry and forest sustainability. Community forest enterprises (CFE) are a heterogeneous group of forest industries managed by indigenous and local communities for livelihood and profit. Many CFEs face inner competitiveness problems,...
This dissertation has two objectives. The first objective is to determine where best to situate the study of mentoring (i.e. the 'making of scientists') on the landscape of the history of science and science studies. This task is accomplished by establishing mentoring studies as a link between the robust body...
Global environmental change is causing local extinctions of species. When species depend on one another, as in the mutualistic relationship between plants and pollinators, loss of one interaction partner may cause cascading effects within the community – such as additional extinctions and reduced pollination services. Network theory provides a way...
Neisseria gonorrhoeae is the sexually transmitted pathogen responsible for millions of cases of gonorrhea worldwide each year. Rapidly-spreading antibiotic resistance is diminishing the ability to effectively treat a disease with significant consequences to female and male reproductive health, as well as to neonatal well-being. A protective vaccine has the potential...