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- Creator:
- Adams, Paul D., Aertgeerts, Kathleen, Bauer, Cary, Bell, Jeffrey A., Berman, Helen M., Bhat, Talapady N., Blaney, Jeff M., Bolton, Evan, Bricogne, Gerard, Brown, David, Burley, Stephen K., Case, David A., Clark, Kirk L., Darden, Tom, Emsley, Paul, Feher, Victoria A., Feng, Zukang, Groom, Colin R., Harris, Seth F., Hendle, Jorg, Holder, Thomas, Joachimiak, Andrzej, Kleywegt, Gerard J., Krojer, Tobias, Marcotrigiano, Joseph, Mark, Alan E., Markley, John L., Miller, Matthew, Minor, Wladek, Montelione, Gaetano T., Murshudov, Garib, Nakagawa, Atsushi, Nakamura, Haruki, Nicholls, Anthony, Nicklaus, Marc, Nolte, Robert T., Padyana, Anil K., Peishoff, Catherine E., Pieniazek, Susan, Read, Randy J., Shao, Chenghua, Sheriff, Steven, Smart, Oliver, Soisson, Stephen, Spurlino, John, Stouch, Terry, Svobodova, Radka, Tempel, Wolfram, Terwilliger, Thomas C., Tronrud, Dale, Velankar, Sameer, Ward, Suzanna C., Warren, Gregory L., Westbrook, John D., Williams, Pamela, Yang, Huanwang, and Young, Jasmine
- Abstract:
- Crystallographic studies of ligands bound to biological macromolecules (proteins and nucleic acids) represent an important source of information concerning drug-target interactions, providing atomic level insights into the physical chemistry of complex formation between macromolecules and ligands. Of the more than 115,000 entries extant in the Protein Data Bank (PDB) archive,...
- Full Text:
- - mented as a validation pipeline used within the wwPDB Deposi- tion and Annotation (D&A) system. A wwPDB
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- Creator:
- Adams, Paul D., Aertgeerts, Kathleen, Bauer, Cary, Bell, Jeffrey A., Berman, Helen M., Bhat, Talapady N., Blaney, Jeff M., Bolton, Evan, Bricogne, Gerard, Brown, David, Burley, Stephen K., Case, David A., Clark, Kirk L., Darden, Tom, Emsley, Paul, Feher, Victoria A., Feng, Zukang, Groom, Colin R., Harris, Seth F., Hendle, Jorg, Holder, Thomas, Joachimiak, Andrzej, Kleywegt, Gerard J., Krojer, Tobias, Marcotrigiano, Joseph, Mark, Alan E., Markley, John L., Miller, Matthew, Minor, Wladek, Montelione, Gaetano T., Murshudov, Garib, Nakagawa, Atsushi, Nakamura, Haruki, Nicholls, Anthony, Nicklaus, Marc, Nolte, Robert T., Padyana, Anil K., Peishoff, Catherine E., Pieniazek, Susan, Read, Randy J., Shao, Chenghua, Sheriff, Steven, Smart, Oliver, Soisson, Stephen, Spurlino, John, Stouch, Terry, Svobodova, Radka, Tempel, Wolfram, Terwilliger, Thomas C., Tronrud, Dale, Velankar, Sameer, Ward, Suzanna C., Warren, Gregory L., Westbrook, John D., Williams, Pamela, Yang, Huanwang, and Young, Jasmine
- Abstract:
- Crystallographic studies of ligands bound to biological macromolecules (proteins and nucleic acids) represent an important source of information concerning drug-target interactions, providing atomic level insights into the physical chemistry of complex formation between macromolecules and ligands. Of the more than 115,000 entries extant in the Protein Data Bank (PDB) archive,...
- Resource Type:
- Article
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- Creator:
- Quentin, Audrey G., Pinkard, Elizabeth A., Ryan, Michael G., Tissue, David T., Baggett, L. Scott, Adams, Henry D., Maillard, Pascale, Marchand, Jacqueline, Landhäusser, Simon M., Lacointe, André, Gibon, Yves, Anderegg, William R. L., Asao, Shinichi, Atkin, Owen K., Bonhomme, Marc, Claye, Caroline, Chow, Pak S., Clément-Vidal, Anne, Davies, Noel W., Dickman, L. Turin, Dumbur, Rita, Ellsworth, David S., Falk, Kristen, Galiano, Lucía, Grünzweig, José M., Hartmann, Henrik, Hoch, Günter, Hood, Sharon, Jones, Joanna E., Koike, Takayoshi, Kuhlmann, Iris, Lloret, Francisco, Maestro, Melchor, Mansfield, Shawn D., Martínez-Vilalta, Jordi, Maucourt, Mickael, McDowell, Nathan G., Moing, Annick, Muller, Bertrand, Nebauer, Sergio G., Niinemets, Ülo, Palacio, Sara, Piper, Frida, Raveh, Eran, Richter, Andreas, Rolland, Gaëlle, Rosas, Teresa, Saint Joanis, Brigitte, Sala, Anna, Smith, Renee A., Sterck, Frank, Stinziano, Joseph R., Tobias, Mari, Unda, Faride, Watanabe, Makoto, Way, Danielle A., Weerasinghe, Lasantha K., Wild, Birgit, Wiley, Erin, and Woodruff, David R.
- Abstract:
- Non-structural carbohydrates (NSC) in plant tissue are frequently quantified to make inferences about plant responses to environmental conditions. Laboratories publishing estimates of NSC of woody plants use many different methods to evaluate NSC. We asked whether NSC estimates in the recent literature could be quantitatively compared among studies. We also...
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- Article
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- Creator:
- Kamoun, Sophien, Furzer, Oliver, Jones, Jonathan D. G., Judelson, Howard S., Ali, Gul Shad, Dalio, Ronaldo J. D., Roy, Sanjoy Guha, Schena, Leonardo, Zambounis, Antonios, Panabières, Franck, Cahill, David, Ruocco, Michelina, Figueiredo, Andreia, Chen, Xiao-Ren, Hulvey, Jon, Stam, Remco, Lamour, Kurt, Gijzen, Mark, Tyler, Brett M., Grünwald, Niklaus J., Mukhtar, M. Shahid, Tomé, Daniel F. A., Tör, Mahmut, Van den Ackerveken, Guido, McDowell, John, Daayf, Fouad, Fry, William E., Lindqvist-Kreuze, Hannele, Meijer, Harold J. G., Petre, Benjamin, Ristaino, Jean, Yoshida, Kentaro, Birch, Paul R. J., and Govers, Francine
- Abstract:
- Oomycetes form a deep lineage of eukaryotic organisms that includes a large number of plant pathogens which threaten natural and managed ecosystems. We undertook a survey to query the community for their ranking of plant-pathogenic oomycete species based on scientific and economic importance. In total, we received 263 votes from...
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- Article
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- , JONATHAN D. G. JONES1, HOWARD S. JUDELSON2, GUL SHAD ALI3, RONALDO J. D. DALIO4, SANJOY GUHA ROY5, LEONARDO
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- Creator:
- Halpern, Benjamin S., Longo, Catherine, Hardy, Darren, McLeod, Karen L., Samhouri, Jameal F., Katona, Steven K., Kleisner, Kristin, Lester, Sarah E., O'Leary, Jennifer, Ranelletti, Marla, Rosenberg, Andrew A., Scarborough, Courtney, Selig, Elizabeth R., Best, Benjamin D., Brumbaugh, Daniel R., Chapin, F. Stuart, Crowder, Larry B., Daly, Kendra L., Doney, Scott C., Elfes, Cristiane, Fogarty, Michael J., Gaines, Steven D., Jacobsen, Kelsey I., Karrer, Leah Bunce, Leslie, Heather M., Neeley, Elizabeth, Pauly, Daniel, Polasky, Stephen, Ris, Bud, St. Martin, Kevin, Stone, Gregory S., Sumaila, U. Rashid, and Zeller, Dirk
- Abstract:
- The ocean plays a critical role in supporting human well-being, from providing food, livelihoods and recreational opportunities to regulating the global climate. Sustainable management aimed at maintaining the flow of a broad range of benefits from the ocean requires a comprehensive and quantitative method to measure and monitor the health...
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- Article
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- , T. D. Linking ecosystem health indicators and collaborative management: a systematic framework to
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- Creator:
- Buizert, Christo, Adrian, Betty, Ahn, Jinho, Albert, Mary, Alley, Richard B., Baggenstos, Daniel, Bauska, Thomas K., Bay, Ryan C., Bencivengo, Brian B., Bentley, Charles R., Brook, Edward J., Chellman, Nathan J., Clow, Gary D., Cole-Dai, Jihong, Conway, Howard, Cravens, Eric, Cuffey, Kurt M., Dunbar, Nelia W., Edwards, Jon S., Fegyveresi, John M., Ferris, Dave G., Fitzpatrick, Joan J., Fudge, T. J., Gibson, Chris J., Gkinis, Vasileios, Goetz, Joshua J., Gregory, Stephanie, Hargreaves, Geoffrey M., Iverson, Nels, Johnson, Jay A., Jones, Tyler R., Kalk, Michael L., Kippenhan, Matthew J., Koffman, Bess G., Kreutz, Karl, Kuhl, Tanner W., Lebar, Donald A., Lee, James E., Marcott, Shaun A., Markle, Bradley R., Maselli, Olivia J., McConnell, Joseph R., McGwire, Kenneth C., Mitchell, Logan E., Mortensen, Nicolai B., Neff, Peter D., Nishiizumi, Kunihiko, Nunn, Richard M., Orsi, Anais J., Pasteris, Daniel R., Pedro, Joel B., Pettit, Erin C., Price, P. Buford, Priscu, John C., Rhodes, Rachael H., Rosen, Julia L., Schauer, Andrew J., Schoenemann, Spruce W., Sendelbach, Paul J., Severinghaus, Jeffrey P., Shturmakov, Alexander J., Sigl, Michael, Slawny, Kristina R., Souney, Joseph M., Sowers, Todd A., Spencer, Matthew K., Steig, Eric J., Taylor, Kendrick C., Twickler, Mark S., Vaughn, Bruce H., Voigt, Donald E., Waddington, Edwin D., Welten, Kees C., Wendricks, Anthony W., White, James W. C., Winstrup, Mai, Wong, Gifford J., and Woodruff, Thomas E.
- Abstract:
- The last glacial period exhibited abrupt Dansgaard–Oeschger climatic oscillations, evidence of which is preserved in a variety of Northern Hemisphere palaeoclimate archives¹. Ice cores show that Antarctica cooled during the warm phases of the Greenland Dansgaard–Oeschger cycle and vice versa[superscript 2,3], suggesting an interhemispheric redistribution of heat through a mechanism...
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- –40 −38 −36 W D C δ 18 O (‰ ) –10 –8 –6 –4 A TS Δ T (° C ) DO
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- Creator:
- Bjorkstedt, Eric P., Goericke, Ralf, McClatchie, Sam, Weber, Ed, Watson, William, Lo, Nancy, Peterson, William T., Brodeur, Richard D., Auth, Toby, Fisher, Jennifer, Morgan, Cheryl, Peterson, Jay, Largier, John, Bograd, Steven J., Durazo, Reginaldo, Gaxiola-Castro, Gilberto, Lavaniegos, Bertha, Chavez, Francisco P., Collins, Curtis A., Hannah, Bob, Field, John, Sakuma, Keith, Satterthwaite, Will, O'Farrell, Michael, Hayes, Sean, Harding, Jeff, Sydeman, William J., Thompson, Sarah Ann, Warzybok, Pete, Bradley, Russell, Jahncke, Jaime, Golightly, Richard T., Schneider, Stephanie R., Suryan, Robert M., Gladics, Amanda J., Horton, Cheryl A., Kim, Sung Yong, Melin, Sharon R., DeLong, Robert L., and Abell, Jeffrey
- Abstract:
- The state of the California Current System (CCS) since spring 2011 has evolved in response to dissipation of La Niña through spring and summer, resurgence of cooler La Niña conditions in fall and winter, and finally a transition towards ENSO-neutral conditions in spring 2012. The resurgence of La Niña was...
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- (venrick et al. 2003). strong ecosystem responses to the intrusion A B C E D F G H I Figure 2
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- Deans, Andrew R., Lewis, Suzanna E., Huala, Eva, Anzaldo, Salvatore S., Ashburner, Michael, Balhoff, James P., Blackburn, David C., Blake, Judith A., Burleigh, J. Gordon, Chanet, Bruno, Cooper, Lauren D., Courtot, Mélanie, Csösz, Sándor, Cul, Hong, Dahdul, Wasila, Das, Sandip, Dececchi, T. Alexander, Dettal, Agnes, Diogo, Rui, Druzinsky, Robert E., Dumontier, Michel, Franz, Nico M., Friedrich, Frank, Gkoutos, George V., Haendel, Melissa, Harmon, Luke J., Hayamizu, Terry F., He, Yongqun, Hines, Heather M., Ibrahim, Nizar, Jackson, Laura M., Jaiswal, Pankaj, James-Zorn, Christina, Köhler, Sebastian, Lecointre, Guillaume, Lapp, Hilmar, Lawrence, Carolyn J., Le Novère, Nicolas, Lundberg, John G., Macklin, James, Mast, Austin R., Midford, Peter E., Mikó, István, Mungall, Christopher J., Oellrich, Anika, Osumi-Sutherland, David, Parkinson, Helen, Ramírez, Martín J., Richter, Stefan, Robinson, Peter N., Ruttenberg, Alan, Schulz, Katja S., Segerdell, Erik, Seltmann, Katja C., Sharkey, Michael J., Smith, Aaron D., Smith, Barry, Specht, Chelsea D., Squires, R. Burke, Thacker, Robert W., Thessen, Anne, Fernandez-Triana, Jose, Vihinen, Mauno, Vize, Peter D., Vogt, Lars, Wall, Christine E., Walls, Ramona L., Westerfeld, Monte, Wharton, Robert A., Wirkner, Christian S., Woolley, James B., Yoder, Matthew J., Zorn, Aaron M., and Mabee, Paula
- Abstract:
- Despite a large and multifaceted effort to understand the vast landscape of phenotypic data, their current form inhibits productive data analysis. The lack of a community-wide, consensus-based, human- and machine-interpretable language for describing phenotypes and their genomic and environmental contexts is perhaps the most pressing scientific bottleneck to integration across...
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- Article
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- , Judith A. Blake9, J. Gordon Burleigh10, Bruno Chanet11, Laurel D. Cooper12, Mélanie Courtot13, Sándor
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- Creator:
- Scavia, Donald, Allan, J. David, Arend, Kristin K., Brandt, Stephen B., Bartell, Steven, Bosch, Nate S., Briland, Ruth D., Daloğlu, Irem, DePinto, Joseph V., Dolan, David M., Evans, Mary Anne, Farmer, Troy M., Goto, Daisuke, Han, Haejin, Höök, Tomas O., Knight, Roger, Ludsin, Stuart A., Mason, Doran, Michalak, Anna M., Richards, R. Peter, Roberts, James J., Rucinski, Daniel K., Rutherford, Edward, Schwab, David J., Sesterhenn, Timothy M., Zhang, Hongyan, and Zhou, Yuntao
- Abstract:
- Relieving phosphorus loading is a key management tool for controlling Lake Erie eutrophication. During the 1960s and 1970s, increased phosphorus inputs degraded water quality and reduced central basin hypolimnetic oxygen levels which, in turn, eliminated thermal habitat vital to cold-water organisms and contributed to the extirpation of important benthic macroinvertebrate...
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- : Central basin hypoxia Scavia, D., David Allan, J., Arend, K. K., Bartell, S., Beletsky, D., Bosch, N. S
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- Creator:
- Manning, Viola A., Pandelova, Iovanna, Dhillon, Braham, Wilhelm, Larry J., Goodwin, Stephen B., Berlin, Aaron M., Figueroa, Melania, Freitag, Michael, Hane, James K., Henrissat, Bernard, Holman, Wade H., Kodira, Chinnappa D., Martin, Joel, Oliver, Richard P., Robbertse, Barbara, Schackwitz, Wendy, Schwartz, David C., Spatafora, Joseph W., Turgeon, B. Gillian, Yandava, Chandri, Young, Sarah, Zhou, Shiguo, Zeng, Qiandong, Grigoriev, Igor V., Ma, Li-Jun, and Ciuffetti, Lynda M.
- Abstract:
- Pyrenophora tritici-repentis is a necrotrophic fungus causal to the disease tan spot of wheat, whose contribution to crop loss has increased significantly during the last few decades. Pathogenicity by this fungus is attributed to the production of host-selective toxins ( HST), which are recognized by their host in a genotype-specific...
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- GGG004044 41..63 INVESTIGATION Comparative Genomics of a Plant