Epigenetic changes, including aberrant DNA methylation, result in altered gene expression and play an important role in
carcinogenesis. Phytochemicals such as sulforaphane (SFN) and 3,3'-diindolylmethane (DIM) are promising chemopreventive
agents for the treatment of prostate cancer. Both have been shown to induce re-expression of genes, including tumor
suppressor genes silenced...
Full Text:
-Sanchez1,2, Laura M. Beaver1,2, E.
Andres Houseman1, David E. Williams2,3, Roderick H. Dashwood2,3, Emily
Summarizes information on wood as an engineering material.
Presents properties of wood and wood-based products
of particular concern to the architect and engineer. Includes
discussion of designing with wood and wood-based products
along with some pertinent uses.
Light-frame construction practices and materials have changed greatly
over the past 100 years. Contemporary research has focused on modern construction; thus, we know a great deal about the behavior of modern lightframe buildings under lateral forces. However, there are many light-frame buildings that were built prior to the introduction of...