Captive rearing programs (hatcheries) are often used in conservation and management efforts
for at-risk salmonid fish populations. However, hatcheries typically rear juveniles in environments
that contrast starkly with natural conditions, which may lead to phenotypic and/or genetic changes that adversely affect the performance of juveniles upon their release to the...
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described by Bø et al., Nucleic Acids Research 2004, 32:e34.
3. Imputed data were read into R and two
Gramene (http://www.gramene.org) is an online resource for comparative functional genomics in crops and model plant species. Its two main frameworks are genomes (collaboration with Ensembl Plants) and pathways (The Plant Reactome and archival BioCyc databases). Since our last NAR update, the database website adopted a new Drupal management platform. The...
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, Sunita Kumari1, Kapeel Chougule1, Justin Elser2, Bo Wang1,
James Thomason1, Daniel M. Bolser3, Arnaud
Management of marine ecosystems increasingly demands comprehensive and quantitative assessments of ocean health,
but lacks a tool to do so. We applied the recently developed Ocean Health Index to assess ocean health in the relatively
data-rich US west coast region. The overall region scored 71 out of 100, with sub-regions...
An Expert Panel convened by the National Lipid Association previously developed a consensus set of recommendations for the patient-centered management of dyslipidemia in clinical medicine (part 1). These were guided by the principle that reducing elevated levels of atherogenic cholesterol (non–high-density lipoprotein cholesterol and low-density lipoprotein cholesterol) reduces the risk...
Plant pathogens secrete an arsenal of small secreted proteins (SSPs) acting as effectors that modulate host immunity to
facilitate infection. SSP-encoding genes are often located in particular genomic environments and show waves of concerted
expression at diverse stages of plant infection. To date, little is known about the regulation of...
As a demonstrator for technologies for the next generation of ocean color sensors,
the Hyperspectral Imager for the Coastal Ocean (HICO) provides enhanced spatial and
spectral resolution that is required to understand optically complex aquatic environments. In
this study we apply HICO, along with satellite remote sensing and in situ...
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. Tufillaro
2
, Raphael M. Kudela
3
and Bo-Cai Gao
4
1
Monterey Bay Aquarium Research Institute
The aim of this work is to review current knowledge relating the established cancer hallmark, sustained cell proliferation
to the existence of chemicals present as low dose mixtures in the environment. Normal cell proliferation is under tight
control, i.e. cells respond to a signal to proliferate, and although most cells...
We report the first systems biology investigation of regulators controlling arterial plaque macrophage transcriptional
changes in response to lipid lowering in vivo in two distinct mouse models of atherosclerosis regression. Transcriptome
measurements from plaque macrophages from the Reversa mouse were integrated with measurements from an aortic
transplant-based mouse model of...
Vibrio cholerae is autochthonous to various aquatic niches and is the etiological agent of the life-threatening diarrheal disease
cholera. The persistence of V. cholerae in natural habitats is a crucial factor in the epidemiology of cholera. In contrast to the
well-studied V. cholerae-chitin connection, scarce information is available about the...
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cholerae with Collagen
Bo R. Park,a Ryszard A. Zielke,a Igor H. Wierzbicki,a Kristie C. Mitchell,b Jeffrey
The Chloroflexi CL500-11 clade contributes a large proportion of the bacterial biomass in the oxygenated hypolimnia of deep lakes worldwide, including the world's largest freshwater system, the Laurentian Great Lakes. Traits that allow CL500-11 to thrive and its biogeochemical role in these environments are currently unknown. Here, we found that...