Dietary restriction (DR) is the gold standard intervention used to delay aging, and much recent research has focused on
the identification of possible DR mimetics. Energy sensing pathways, including insulin/IGF1 signaling, sirtuins, and
mammalian Target of Rapamycin (mTOR), have been proposed as pathways involved in the antiaging actions of DR,...
Full Text:
and rapamycin on glucose
and insulin tolerance test. The GTT (A) and ITT (B) were performed as
Dietary restriction (DR) is the gold standard intervention used to delay aging, and much recent research has focused on
the identification of possible DR mimetics. Energy sensing pathways, including insulin/IGF1 signaling, sirtuins, and
mammalian Target of Rapamycin (mTOR), have been proposed as pathways involved in the antiaging actions of DR,...
Full Text:
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Dietary restriction (DR) is the gold standard intervention used to delay aging, and much recent research has focused on
the identification of possible DR mimetics. Energy sensing pathways, including insulin/IGF1 signaling, sirtuins, and
mammalian Target of Rapamycin (mTOR), have been proposed as pathways involved in the antiaging actions of DR,...
Repetitive sequences present a challenge for genome sequence assembly, and highly similar segmental duplications may
disappear from assembled genome sequences. Having found a surprising lack of observable phenotypic deviations and
non-Mendelian segregation in Arabidopsis thaliana mutants in SEC10, a gene encoding a core subunit of the exocyst
tethering complex, we...
Repetitive sequences present a challenge for genome sequence assembly, and highly similar segmental duplications may
disappear from assembled genome sequences. Having found a surprising lack of observable phenotypic deviations and
non-Mendelian segregation in Arabidopsis thaliana mutants in SEC10, a gene encoding a core subunit of the exocyst
tethering complex, we...
Full Text:
Vukašinović, N., Cvrčková, F., Eliáš, M., Cole, R., Fowler, J. E., et al. (2014)
Dissecting a Hidden Gene
Using genetic approaches, particle image velocimetry and an inert tracer of cytoplasmic streaming, we have made a mechanistic connection between the motor proteins (myosins XI), cargo transported by these motors (distinct endomembrane compartment defined by membrane-anchored MyoB receptors) and the process of cytoplasmic streaming in plant cells. It is shown...
Repetitive sequences present a challenge for genome sequence assembly, and highly similar segmental duplications may disappear from assembled genome sequences. Having found a surprising lack of observable phenotypic deviations and non-Mendelian segregation in Arabidopsis thaliana mutants in SEC10, a gene encoding a core subunit of the exocyst tethering complex, we...
Six high-use destination areas were studied in the Alpine Lakes, Mount Jefferson, and Three Sisters Wildernesses in Washington and Oregon. Exit interviews were conducted with visitors, and recreation impacts and visitor encounter rates between groups were quantified. Encounter rates were extremely high and impacts were substantial but localized. Visitors were...
The behavior and application of organic semiconductor materials depend strongly on their molecular structure, and molecular interactions. Several studies of intermolecular interactions in functionalized polyacene materials are presented. The degree and onset of aggregation of a functionalized anthradithiophene derivative was studied as a function of concentration in two different host...
Pacific sardines (Sardinops sagax) are an economically and ecologically important forage fish which transfer energy from planktonic primary producers and secondary consumers to upper trophic predators. Previous genetics studies of Pacific sardine suggested a panmictic population with a shallow genetic structure. However, more than one subpopulation within the Central California...