The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that plays multiple roles in regulation of immune and inflammatory responses. The ability of certain AhR ligands to induce regulatory T cells (Tregs) has generated interest in developing AhR ligands for therapeutic treatment of immune-mediated diseases. To this end, we...
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that plays multiple roles in regulation of immune and inflammatory responses. The ability of certain AhR ligands to induce regulatory T cells (Tregs) has generated interest in developing AhR ligands for therapeutic treatment of immune-mediated diseases. To this end, we...
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Pennington1,
Diana Rohlman1, Edmond O’Donnell1, Patrick L. Iversen1, Siva Kumar Kolluri1,2, Nancy I
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that plays multiple roles in regulation of immune and inflammatory responses. The ability of certain AhR ligands to induce regulatory T cells (Tregs) has generated interest in developing AhR ligands for therapeutic treatment of immune-mediated diseases. To this end, we...
This text was written for the purpose of explaining the use of the engineer's transit, theodolite, engineer's level and plane table in the solution of fundamental problems related to Forest Engineering. While the use of the infrared and electronic distance measuring instruments do have a place in Forest Engineering, they...
Non-coding ribonucleic acid (ncRNA) is of interest for its diverse roles in cell and viral biology. RNA molecules vary greatly in terms of size, structure, and function. In recent years, the modification of existing RNA structures has been used for biochemical methods of enormous impact including CRISPR and RNAi methods....
Premature birth interrupts the typical development of the human fetus, leaving the infant born with underdeveloped gastrointestinal and immune systems. Preterm infants have reduced stomach acidity, reduced digestive protease activity, more permeable intestinal membranes, impaired innate and adaptive immune response, and poor microbiome development. Due to these factors, preterm infants...