Introduction. Age is the primary risk factor for major human chronic diseases, including cardiovascular disorders, cancer, type 2 diabetes, and neurodegenerative diseases. Chronic, low-grade, systemic inflammation is associated with aging and the progression of immunosenescence. Immunosenescence may play an important role in the development of age-related chronic disease and the...
Full Text:
. Science 331:337–341 DOI 10.1126/science.1198469.
Belzer C, Gerber GK, Roeselers G, DelaneyM, DuBois A
Signal transduction within and between cells is at the core of biological activity in all living systems. Signaling networks are required for regulating biological functions, including growth, development and survival. Deregulation of signaling cascades has been linked to chronic and acute diseases and disorders This thesis focuses on mass spectrometry...
The reason for the initial rise in atmospheric
CO₂ during the last deglaciation remains unknown. Most recent
hypotheses invoke Southern Hemisphere processes such
as shifts in midlatitude westerly winds. Coeval changes in
the Atlantic meridional overturning circulation (AMOC) are
poorly quantified, and their relation to the CO₂ increase is
not...
Full Text:
) components in (G) and (H), following Schmittner et al. (2014). All anomalies are shown relative
to model
The rugged Cascade Range of central Oregon has been long regarded as an enigmatic, archaeological puzzle in the study of the Pacific Northwest's ancient past. While ethnographic and archaeological research in the adjacent northern Great Basin, Columbia Plateau and Willamette Valley have revealed a rich and ancient tapestry of Native...
Full Text:
used for sewing or puncturing animal skins and/or other textiles.
L -WI-!"1 P] -A-3-3 91-A-5-h
06