Mantel-based tests have been the primary analytical methods for understanding how landscape features influence observed spatial genetic structure. Simulation studies examining Mantel-based approaches have highlighted major challenges associated with the use of such tests and fueled debate on when the Mantel test is appropriate for landscape genetics studies. We aim...
Bud dormancy in grapevine is an adaptive strategy for the survival of drought, high and low temperatures and freeze dehydration stress that limit the range of cultivar adaptation. Therefore, development of a comprehensive understanding of the biological mechanisms involved in bud dormancy is needed to promote advances in selection and...
Vitamin E improved liver histology in children and adults with NAFLD who participated in TONIC and PIVENS clinical trials, but with significant inter-individual variability in its efficacy. Cytochrome P450 4F2 (CYP4F2) is the major enzyme metabolizing Vit E, with two common genetic variants (V433M, rs2108622 and W12G, rs3093105) found to...
Objective
Our objective was to use episodic memory and executive function tests to determine whether or not Chiari Malformation Type I (CM) patients experience cognitive dysfunction.
Background
CM is a neurological syndrome in which the cerebellum descends into the cervical spine causing neural compression, severe headaches, neck pain, and number...
The metabolic theory of ecology (MTE) predicts the effects of body size and temperature on metabolism through considerations of vascular distribution networks and biochemical kinetics. MTE has also been extended to characterise processes from cellular to global levels. MTE has generated both enthusiasm and controversy across a broad range of...
BACKGROUND: Targeted capture of genomic regions reduces sequencing cost while generating higher coverage by
allowing biomedical researchers to focus on specific loci of interest, such as exons. Targeted capture also has the
potential to facilitate the generation of genomic data from DNA collected via saliva or buccal cells. DNA samples...
Full Text:
,
Xiaosen Guo9, Qiang Feng9, Yingrui Li9, Xiao Liu9, Peter Parham6, Eileen G Hoal10, Marcus W Feldman11
BACKGROUND: Targeted capture of genomic regions reduces sequencing cost while generating higher coverage by
allowing biomedical researchers to focus on specific loci of interest, such as exons. Targeted capture also has the
potential to facilitate the generation of genomic data from DNA collected via saliva or buccal cells. DNA samples...
BACKGROUND: Targeted capture of genomic regions reduces sequencing cost while generating higher coverage by
allowing biomedical researchers to focus on specific loci of interest, such as exons. Targeted capture also has the
potential to facilitate the generation of genomic data from DNA collected via saliva or buccal cells. DNA samples...
Full Text:
Guadalupe8, Xiaosen Guo9, Qiang Feng9,
Yingrui Li9, Xiao Liu9, Peter Parham6, Eileen G. Hoal10, Marcus W
Much uncertainty exists about the state of the oceanic and atmospheric circulation in the tropical Pacific over the last glacial cycle. Studies have been hampered by the fact that sediment cores suitable for study were concentrated in the western and eastern parts of the tropical Pacific, with little information from...
BACKGROUND: Targeted capture of genomic regions reduces sequencing cost while generating higher coverage by
allowing biomedical researchers to focus on specific loci of interest, such as exons. Targeted capture also has the
potential to facilitate the generation of genomic data from DNA collected via saliva or buccal cells. DNA samples...