Perinatal growth restriction programs higher risk for chronic disease during adulthood
via morphological and physiological changes in organ systems. Perinatal growth
restriction is highly correlated with a decreased nephron number, altered renal function
and subsequent hypertension. We hypothesize that such renal maladaptations result in
altered pharmacologic patterns for life. Maternal...
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furosemide in
adult rats
DuBois, B. N., Pearson, J., Mahmood, T., Nguyen, D., Thornburg, K., & Cherala,
G
Resource managers at the state, federal, and tribal levels make decisions on a weekly to quarterly basis, and fishers operate on a similar timeframe. To determine the potential of a support tool for these efforts, a seasonal forecast system is experimented with here. JISAO’s Seasonal Coastal Ocean Prediction of the...
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, ALBERT J. HERMANN (albert.j.hermann@noaa.gov)1,6,
THANH TAM NGUYEN (nttam15@uw.edu)1, NICHOLAS A. BOND
Resource managers at the state, federal, and tribal levels make decisions on a weekly to quarterly basis, and fishers operate on a similar timeframe. To determine the potential of a support tool for these efforts, a seasonal forecast system is experimented with here. JISAO’s Seasonal Coastal Ocean Prediction of the...
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. Bond1,3, Jan A. Newton4, Gregory D. Williams5, William T. Peterson6,
Simone R. Alin3 & Richard A. Feely3
Mammalian flavin-containing monooxygenase (FMO) is active towards many drugs with a heteroatom having the properties of a soft nucleophile. Thiocarbamides and thiones are S-oxygenated to the sulfenic acid which can either react with glutathione and initiate a redox-cycle or be oxygenated a second time to the unstable sulfinic acid. In...
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interesting genetic polymorphism
exists in humans. Caucasians and Asians carry a C→T transition mutation
The ovine sexually dimorphic nucleus (oSDN) is 2 times larger in rams than in ewes. Sexual
differentiation of the oSDN is produced by testosterone exposure during the critical period
occurring between gestational day (GD)60 and GD90 (term, 147 d). We tested the hypothesis
that testosterone acts through the androgen receptor...
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, C. T., Scheldrup, M., Meaker, M., Stormshak,
F., & Montilla, H. J. (2014). Prenatal Influence of an
From a screen of 36 plant-associated strains of Burkholderia spp., we identified 24 strains that suppressed leaf and pseudobulb necrosis of orchid caused by B. gladioli. To gain insights into the mechanisms of disease suppression, we generated a draft genome sequence from one suppressive strain, TC3.4.2R3. The genome is an...
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. gladioli
Welington L. Araújo,1 Allison L. Creason,2,3 Emy T. Mano,1 Aline A. Camargo-Neves,1,4
Sonia N
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that plays multiple roles in regulation of immune and inflammatory responses. The ability of certain AhR ligands to induce regulatory T cells (Tregs) has generated interest in developing AhR ligands for therapeutic treatment of immune-mediated diseases. To this end, we...
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of certain AhR ligands to induce regulatory T cells (Tregs) has generated
interest in developing AhR
The World Summit on Sustainable Development (Johannesburg, 2002)
encouraged the application of the ecosystem approach by 2010.
We propose a framework that deals jointly with i) ecosystem dynamics,
ii) conflicting issues of production and preservation and
iii) robustness with respect to dynamics uncertainties.
More specifically, we define robust viability kernels...
Controversial end member models for the growth and evolution of the Tibetan Plateau demand quantitative constraints of the lithospheric rheology. Direct determinations of bulk crustal rheology, however, remain relatively sparse. Here we use the flexural rebound of lacustrine shorelines developed during the Lingtong highstand around Siling Co, in central Tibet,...
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time that is approximately 1/3 of the total 275
relaxation time (τT) (Turcotte and Schubert, 2002