The zebrafish (Danio rerio) is emerging as a new important species for studying brain mechanisms and its deficits. Focusing on selected CNS disorders (brain cancer, epilepsy and anxiety) and using them as examples, we discuss the value of zebrafish models in translational neuroscience, and their contribution to neuroimaging, circuit-level and...
Mantel-based tests have been the primary analytical methods for understanding how landscape features influence observed spatial genetic structure. Simulation studies examining Mantel-based approaches have highlighted major challenges associated with the use of such tests and fueled debate on when the Mantel test is appropriate for landscape genetics studies. We aim...
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).
Conflict of Interest
None declared.
References
Adriaensen, F., J. P. Chardon, G. De Blust, E. Swinnen, S
Mantel-based tests have been the primary analytical methods for understanding how landscape features influence observed spatial genetic structure. Simulation studies examining Mantel-based approaches have highlighted major challenges associated with the use of such tests and fueled debate on when the Mantel test is appropriate for landscape genetics studies. We aim...
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matrix that will hold pairwise cost distances
for(j in 1:no.individuals) { # loop through pairs of
A recombinant inbred line (RIL) mapping population developed from a cross between winter wheat (Triticum aestivum L.)
cultivars Coda and Brundage was evaluated for reaction to stripe rust (caused by Puccinia striiformis f. sp. tritici). Two
hundred and sixty eight RIL from the population were evaluated in replicated field trials...
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Population
Austin J. Case1¤, Yukiko Naruoka1, Xianming Chen2, Kimberly A. Garland-Campbell2, Robert S
Only two genome-wide significant loci associated with longevity have been identified so far, probably because of insufficient sample sizes of centenarians, whose genomes may harbor genetic variants associated with health and longevity. Here we report a genome-wide association study (GWAS) of Han Chinese with a sample size 2.7 times the...
Joseph Reddeford Walker conducted
a party of men across the Sierra Nevada to the
Pacific coast of California in 1833. Previous
interpretations of the portion of the route
from Humboldt Sink, Nevada, to the San Joaquin
River, California, are not satisfactory. A
body of descriptions of the terrain traversed
exists...
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securing and furnishing horses to the fur traders at Inde-
pendence, Walker met with Captain Benjamin L. E
We report zero kinetic energy (ZEKE) photoelectron spectroscopy of benzo[h]quinoline (BhQ) via resonantly enhanced multiphoton ionization (REMPI) through the first electronically excited state S₁. From the simulated REMPI spectra with and without Herzberg–Teller coupling, we conclude that vibronic coupling plays a minor but observable role in the electronic excitation to...
We report zero kinetic energy (ZEKE) photoelectron spectroscopy of benzo[a]pyrene (BaP) via resonantly enhanced multiphoton ionization (REMPI). Our analysis concentrates on the vibrational modes of the first excited state (S₁) and those of the ground cationic state (D₀). Similar to pyrene, another peri-condensed polycyclic aromatic hydrocarbon we have investigated, the...
We report vibrational information of both the first electronically excited state and the ground
cationic state of jet-cooled triphenylene via the techniques of resonantly enhanced multiphoton
ionization (REMPI) and zero kinetic energy (ZEKE) photoelectron spectroscopy. The first excited
electronic state S₁ of the neutral molecule is of A₁' symmetry and...
A major issue in non-inferiority trials is the controversial assumption of constancy,
namely that the active control has the same effect relative to placebo as in previous studies
comparing the active control with placebo. The constancy assumption is often in doubt, which
has motivated various methods that ‘discount’ the control...
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-inferiority Trials 17
(e) μj ∼N.0, 0:52/, β0Wj ∼N.0, 0:252/ and β1Wj ∼N.0, 0:252/, independently of each