Molecular genetic and enzymological techniques have been employed to study secondary metabolite biosynthesis. These investigations have focused on two projects: the cloning and heterologous expression of biosynthetic gene clusters from unculturable marine organisms and the characterization of individual enzymes involved in the biosynthesis of the antifungal agent blasticidin S. The...
Objectives: To identify the perceptions of community hospital physicians on computerized physician order entry. Design: Multi-method approach consisting of a mail survey of 659 community hospital physicians with active admitting privileges at three PeaceHealth, Inc., along with follow-up personal interviews with stratified random selection from completed survey. Measurements: Perceptions were...
Estuaries are once again emerging as important ecosystems for scientific study. Consequently, knowledge of what research has been conducted helps us identify benchmarks and plan new projects. A comprehensive bibliography of published research, technical reports, local documents, and data sets is one means of recording this knowledge. Yaquina Bay, located...
Breast cancer is the leading cancer in women with an estimated 13% of women in the United States developing a form of invasive breast cancer in her lifetime. The survival rate is estimated to be 85%, but the American Cancer Society estimates that early detection of breast cancer in the...
There Were Bears and Rumors of Bears is a collection of stories that explores spiritual injury and recovery using a variety of interior and exterior narrative approaches to depict the profane and sacred, the mundane and non-ordinary, aspects of experience. In each story, the characters encounter situations in the physical...
An expedient approach to the synthesis of a wide range of highly programmable biaryl templates has been accomplished. Utilizing the Diels-Alder [4+2] cycloaddition, a wide range of tri- and tetra-ortho-substituted biaryls have been synthesized in only three to four steps from commercially available materials. We have successfully synthesized entire classes...
Summarizes information on wood as an engineering material.
Presents properties of wood and wood-based products
of particular concern to the architect and engineer. Includes
discussion of designing with wood and wood-based products
along with some pertinent uses.
All animals have developed the critical ability to detect, respond to, and detoxify a large array of environmental chemicals and stressors that can cause adverse health effects. Important examples of landmark contaminants around the world are polycyclic aromatic hydrocarbons (PAHs) and dioxins, both of which can act via the aryl...