Neisseria gonorrhoeae is the sexually transmitted pathogen responsible for millions of cases of gonorrhea worldwide each year. Rapidly-spreading antibiotic resistance is diminishing the ability to effectively treat a disease with significant consequences to female and male reproductive health, as well as to neonatal well-being. A protective vaccine has the potential...
People will spend a large amount of their lifetime indoors where the air is filled with both indoor and outdoor allergens. Exposure to allergens can have a range of effects on the health of building occupants. Textiles make up a vast majority of the surfaces, such as draperies, sofas, pillows,...
T cells are one of the key cells in the immune system. Although they are not the first line of defense against a pathogen, their functions can greatly enhance the phagocytosis and destruction of pathogens as well as the development of antibody responses. Furthermore, even when responding T cells have...
Symbiosis is the close and protracted interaction between organisms. The molecular interactions that occur during symbiosis are complex with multiple barriers that must be overcome. Many Gram-negative, host-associated bacteria use a type III secretion system to mediate associations with their eukaryotic hosts. This secretion system is a specialized apparatus for...
Columbia River Basalt Group dikes cut the tonalite-granodiorite Wallowa Batholith in northeastern Oregon, providing a natural setting in which to examine partial melting. Many dikes have up to 5 m-wide zones of quenched partially melted wallrock at their margins. This paper examines the progressive partial melting reactions in biotite-and hornblende-bearing...
Proteins are the metabolic machines of the cell and as such, the study of proteins could illuminate the dominant biological activities that are occurring within cells and reveal how an organism interacts with its environment. Here, we used proteomic techniques to study the abundant marine bacterium SAR11 both as an...
The primary goal of this study is to assess the impact of a subduction component
added to the mantle wedge beneath the Oregon Cascades to the composition and fO2 of
primitive Cascade basalts. Olivine-hosted melt inclusions from compositionally diverse
basalts across the Cascade arc (~100 km) are utilized in an...
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lavas where
volcanic gasses are lost during eruption.
In this study we report an example of Fe
My work has focused on investigating synthetic organic reactions using applied computational methods. Non-covalent interactions are critical to catalysis, mechanism, and stereoselectivity, with the most prominent interaction for isothioureas being the S···O contact between the catalyst sulfur atom and the oxygen of the acyl group. A comprehensive joint experimental and...
Heterogeneous catalysis modulates the rate and selectivity of reaction processes by
stabilizing a series of intermediate states on solid surfaces, facilitating the production
of many commodity chemicals modern society relies upon. Conventional, thermal
catalytic processes—conducted at elevated temperatures and pressures—source
thermal, mechanical, and chemical potential energy from carbon-hydrogen bonds—
combustion...