BACKGROUND: Arsenic is an epigenetic toxicant and could influence fetal developmental programming.
OBJECTIVES: We evaluated the association between arsenic exposure and DNA methylation in maternal and umbilical cord leukocytes.
METHODS: Drinking-water and urine samples were collected when women were at <= 28 weeks gestation; the samples were analyzed for arsenic...
Wildfires are increasing in frequency. One area of research interest centers on the pollutants within wildfire smoke, including but not limited to particulate matter and polycyclic aromatic hydrocarbons. These chemicals are associated with exacerbation of respiratory, cardiovascular, dermatological, reproductive, oncological, gastrointestinal, and infectious conditions. As wildfires becoming increasingly prevalent, it...
Ubiquitous fine particulate matter (PM2.5) exposures significantly impact global public health, yet little is known about the mechanisms causing these known adverse health effects. Oxidative stress due to PM2.5 associated chemical constituents, such as polycyclic aromatic hydrocarbons (PAHs), is a proposed possible mechanism for PM2.5 mediated health effects. Variations in...
Polycyclic aromatic hydrocarbons (PAHs) are widespread environmental contaminants that occur in complex mixtures. These environmental mixtures can consist of both parent PAHs and their derivatives. Several parent PAHs are known or suspected mutagens and/or carcinogens, and a handful of PAH derivatives are known to be more potent mutagens and/or carcinogens...
Throughout their lifetime individuals are exposed to complex mixtures of chemicals. The study of chemical mixtures is an internationally recognized research priority, but seemingly complex challenge. To reduce the intricacy of studying mixtures, researchers have identified different prioritization methods based on exposure or the toxicity of chemicals. However, understanding the...
In the past fifty years, per- and polyfluoroalkyl substances (PFASs) have become alarming global pollutants. In 2019, the United States (U.S.) Environmental Protection Agency (EPA) ultimately classified them as emerging contaminants and established an action plan to address PFAS and protect public health through developing, identifying, monitoring, and remediating current...
The discovery of new blue pigments is a field of great interest, as commercially available pigments present properties that make them undesirable such as poor sustainability, cost, and stability. By researching solid solutions with the melilite structure, we discovered a new solid solution Sr2Zn1-xNixGe2O7, with 0.1 ≤ x ≤ 0.6,...
Terrestrial land use activities present cross-ecosystem threats to riverine and marine species and processes. Specifically, pesticide runoff can disrupt hormonal, reproductive, and developmental processes in aquatic organisms, yet non-point source pollution is difficult to trace and quantify. In Oregon, U.S.A., state and federal forestry pesticide regulations, designed to meet regulatory...
Nowadays selective separation processes are sought after more than ever before. They are indispensable to meet the growing demand for individual rare earth elements, minor actinides partitioned from fission-produced lanthanides, as well as, overall, more concentrated and high-purity products. This research focuses on such separation techniques as solvent extraction which...
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Figure 1.3 Extractant Molecules Used for Development of ALSEP Process: (A)
HEH[EHP], (B
Climate change is causing people around the world to experience extreme temperature and air pollution events such as wildfires more frequently, and for longer periods of time. Extreme heat events have been widely associated with an increased risk of emergency room visits, occupational heat-related injuries and illnesses, and mortality overall...