Reporter gene transactivation by human p53 is inhibited in budding yeast lacking the TRR1 gene encoding thioredoxin reductase. Thioredoxin reductase specifically catalyzes the NADPH-dependent reduction of thioredoxin. Thioredoxin provides a source of electrons for disulfide reduction in various cellular processes. Reduction of disulfides within the cell can be accomplished by...
In recent years, RF (Radio Frequency) device fingerprinting using deep learning has emerged as a method of identifying devices solely by their RF transmissions. Conventional approaches to this type of device fingerprinting are not portable to different domains. That is, if a model for this purpose is trained on data...
Xanthohumol, a prenylated flavonoid found in hops and beer, possesses a long-standing reputation to improve health. Xanthohumol’s cytotoxicity to a wide variety of cancer cell lines is well-established. Herein we provide further insight into the cytotoxicity of not only xanthohumol, but also its non-estrogenic derivatives, to a number of colonic...
Ian Angell, in the New Barbarian Manifesto, said “A ‘brave new world’ is being forced upon unsuspecting societies by advances in information technology.” It would seem then, that technological advances happen automatically and have a life of their own. There is a logic to technological advancements that is outside human...
Analysis of satellite ocean color, sea surface temperature, and sea ice cover data reveals consistent patterns between biological production, iron availability, and physical forcings in the Southern Ocean. The consistency of these patterns, in conjunction with information on physical conditions during the last glacial maximum (LGM), enables estimates of export...
The research examines the effect of restricted head and neck movement on
driving performance as measured by decision time at T-intersections. The traffic
safety and human factors literature was reviewed, and very little was found
concerning drivers with physical limitations. T-intersections were selected for
study because most accidents involving drivers...