The work described herein details the synthesis and application of
biphenyls that probe the effects of hydrogen, Cl / Br, and methyl substituents
on the aryl ring of the terminal acetylenic carbon. From this work, we
successfully developed the rapid synthesis of phenyl acetylenes in 3-4 steps
from inexpensive commercially...
The isothiocyanate sulforaphane is a promising molecule for development as a therapeutic agent for patients with metastatic
prostate cancer. Sulforaphane induces apoptosis in advanced prostate cancer cells, slows disease progression in vivo and is well
tolerated at pharmacological doses. However, the underlying mechanism(s) responsible for cancer suppression remain to be...
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cancer cells. Cancer Res 2000; 60: 1426–1433.
8 Pham NA, Jacobberger JW, Schimmer AD, Cao P, Gronda M
This study was undertaken to determine the sorts of polygalacturonases
present in the culture filtrate of Fusarium oxysporum
f. sp. lycopersici, to purify and characterize these enzymes, and to
study any complexes that may form between polygalacturonase and
carbohydrate not degraded by the enzyme.
The polygalacturonase in culture filtrate consists...
Nalidixic acid and its derivatives act through inhibition of
bacterial DNA gyrase activity. Recently there have been a series of
papers reporting the antibacterial activity against three different
types of bacteria (S. aureus, E. coli and P. aeruginosa) by a series
of 1,4-dihydro-4-oxoquinoline (or 1,8-naphthyridine) 3-carboxylic
acids. Consistent biological data...
Urban agriculture (UA) is defined as the production of food crops or livestock within urban areas. Despite its popularity in the United States, research into UA systems suffers from a general underrepresentation of commercial urban systems. As a result, urban growers often have unique technological needs that are unmet by...
Assessments of climate change over time scales that exceed the last 100 years require robust integration of high-quality instrument records with high-resolution paleoclimate proxy data. In this study, we show that the recent biogenic sediments accumulating in two temperate ice-free fjords in Southeast Alaska preserve evidence of North Pacific Ocean...
Global vegetation models require the photosynthetic parameters, maximum carboxylation capacity (V[subscript cm]), and quantum yield (alpha) to parameterize their plant functional types (PFTs). The purpose of this work is to determine how much the scaling of the parameters from leaf to ecosystem level through a seasonally varying leaf area index...
Morphology of Actinidia arguta (Sieb. et Zucc) Miq. 'Ananasnaya' vines was studied at two sites in Oregon in 1998 and one site in 1999. Three-year-old vines at site 1 and 8-year-old vines at site 2 were observed. Five types of fruiting wood were studied: spur; one-year-old from the cordon, from...