The immune system is a complex network of cellular processes working in harmony to guard us against pathogenic attack. Of utmost importance is the ability of the immune system to discriminate between “self” and “non-self” and diseased versus healthy. Recognition of antigens complexed to major histocompatibility complex (MHC) molecules is...
Autoinduction (AI), the response to self-produced chemical signals,
is widespread in the bacterial world. This process controls
vastly different target functions, such as luminescence, nutrient
acquisition, and biofilm formation, in different ways and integrates
additional environmental and physiological cues. This diversity
raises questions about unifying principles that underlie all
AI...
The potential for nanomedicine to reduce toxicity and improve therapeutic response to radiation is vast. Clinically, this potential has thus far only begun to be realized with the recent success of the radioenhancing nanoparticle, NBTXR3 by Nanobiotix. Radioenhancing nanoparticles, however, represent only a small class of nanomaterials that may be...
Retrievals of cloud properties from satellite imagery often invoke the assumption that the fields of view are overcast when cloud-contaminated, even though a significant fraction are only partially cloud-covered. The overcast assumption leads to biases in the retrieved cloud properties: cloud amounts and droplet effective radii are typically overestimated, while...
Advanced Very High Resolution Radiometer (AVHRR) 4-km data collected over the northeastern Atlantic off the coast of the Iberian Peninsula for May to August 1995 were used to investigate the feasibility of empirically deriving estimates of the aerosol indirect radiative forcing. A retrieval scheme was used to derive cloud visible...
Advanced Very High Resolution Radiometer (AVHRR) 4-km data were collected over the northeast Atlantic for May–August 1995–1999. Aerosol optical depth at 0.55 μm was retrieved in pixels identified as being cloud-free ocean. In pixels identified as containing clouds from single-layered, low-level cloud systems over oceans, the following cloud properties were...
A time history of the calibration coefficients for channels 1 and 2 of the Advanced Very High Resolution Radiometer (AVHRR) on the NOAA-12 and NOAA-15 spacecraft is presented. The history is based on reflectances observed for the interior zones of the Antarctic and Greenland ice sheets previously obtained with the...
Reproductive and endocrine disruption is commonly reported in aquatic species exposed to complex contaminant mixtures. We previously reported that Atlantic killifish (Fundulus heteroclitus) from the chronically contaminated Newark Bay, NJ, exhibit multiple endocrine disrupting effects, including inhibition of vitellogenesis (yolk protein synthesis) in females and false negative vitellogenin biomarker responses...
Clouds and the Earth’s Radiant Energy System (CERES) uses a suite of instruments on the Terra and Aqua satellites combined with analyzed weather data and information on surface conditions to estimate surface radiative fluxes. CERES estimates for the Terra satellite were compared with measurements of the surface radiative fluxes collected...