Intact and ovariectomized (OVX) pony mares were randomly assigned to treatments of morphine (M), naloxone (N), or a saline control (C) to determine if endogenous opioid peptides (EOP) play a role in equine seasonal breeding. Morphine was expected to decrease luteinizing hormone (LH), whereas N (an opiate antagonist) should in...
1-Phenyl-3-(2-Thiazoly1)-2-Thiourea (PTTU), has been reported to
inhibit dopamine-fi-hydroxylase (a copper-containing enzyme involved in
the pathway of biosynthesis of adrenaline in animal systems). In the
present study, PTTU has been shown to have cytokinin activity in the
tobacco bioassay. The cytokinin activity of PTTU suggested that
cytokinin-active N⁶-substituted adenine derivatives might...
Hexachlorophene (HCP; 2,2'-methylenebis-(3,4,6-trichlorophenol))
was developed as an antibacterial agent but was also found to induce
toxic effects in various tissues in animals and humans. Changes were
found in myelinated nerve fibers and cerebral white matter. Erythrocytes
are hemolysed in vitro. Oxidative phosphorylation is uncoupled
by HCP at concentrations less than...
Three highly purified forms of cytochrome P-450 (P-450a, P-450b, P-450c) from Aroclor 1254-induced rat hepatic microsomes catalyzed the monooxygenation of 1-(2- chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea (MeCCNU) and 1-(2-chloroethyl)-3-(cyclohexyl)-1-nitrosourea (CCNU) in the presence of purified NADPH cytochrome P-450 reductase, NADPH and oxygen. Cytochrome P -450- dependent monooxygenation of CCNU gave six alicyclic hydroxylation products...
The behavioral repertoire of the sea anemone, Anthopleura
xanthogrammica, was investigated to test for the occurrence of any
immediate response to various regions of the electromagnetic spectrum.
Monochromatic radiations in the visible and ultraviolet spectral
regions were produced by a 150-watt xenon lamp or a ZOO watt mercury
vapor lamp...
Aflatoxins B₁, Q₁ and aflatoxicol, R [subscript o] F, but not B₂ were activated in the presence of NADPH by the 105,000 x g pellet from rainbow
trout (Salmo gairdneri), Mt. Shasta strain, liver to products lethal to
Bacillus subtilis GSY 1057 (metB4, hisAl, uvr-1). Electron microscopy
confirmed the microsomal...
An aspect of the metabolism of monoalkylhydrazines has been
investigated using both intact rats and rat liver microsomal enzyme
preparations.
Intact rats respired propane and n-butane on administration of 0.3-0.5 mmoles of isopropyl- and n-butylhydrazine, respectively.
Based upon dose administered, a five to ten percent
yield of hydrocarbon was obtained....
The objectives of this study include: (1) analysis of Chamaecyparis
lawsoniana, C. taiwanensis, and C. formosensis forests including
the structure, composition, and dynamics of plant communities and
their environmental relationships; and (2) comparison of the temperate
Chamaecyparis forests of Taiwan and the Pacific Northwest with emphasis
on structural and successional...