This report is one of a series issued in cooperation with the ANC-23 Panel on Composite Construction for Flight Vehicles of the Departments of the Air Force, Navy, and Commerce.
Restricted rotations of chemical bonds can lead to the presence of persistent conformational chirality in molecules 10 lacking stereocenters. We report the development of first-ofa- kind predictive rules that enable identification of conformational chirality and prediction of racemization barriers in the diarylether heptanoid (DAEH) natural products that do not possess...
Frailty is a state of decreased physical functioning and a significant complication of ageing. We examined frailty, energy and macronutrient
intake, biomarkers of nutritional status and food insufficiency in US older adult (age ≥60 years) participants of the Third National Health
and Nutrition Examination Survey (n 4731). Frailty was defined...
Introduction: People whose faces look untrustworthy tend to receive harsher social evaluations, including more severe criminal sentences. Yet little is known about how much facial trustworthiness reflects individuals’ behavioral histories. We examined whether adolescent histories of delinquency and substance use predict strangers’ perceptions of young men’s facial trustworthiness. Methods: Boys...
It is difficult to relate intrinsic nanomaterial properties to their functional behavior in the environment. Unlike frameworks for dissolved organic chemicals, there are few frameworks comparing multiple and inter-related properties of engineered nanomaterials (ENMs) to their fate, exposure, and hazard in environmental systems. We developed and evaluated reproducibility and inter-correlation...
Successful host cell colonization by the Q fever pathogen, Coxiella burnetii, requires translocation of effector proteins into
the host cytosol by a Dot/Icm type 4B secretion system (T4BSS). In Legionella pneumophila, the two-component system (TCS)
PmrAB regulates the Dot/Icm T4BSS and several additional physiological processes associated with pathogenesis. Because PmrA...
Successful host cell colonization by the Q fever pathogen, Coxiella burnetii, requires translocation of effector proteins into
the host cytosol by a Dot/Icm type 4B secretion system (T4BSS). In Legionella pneumophila, the two-component system (TCS)
PmrAB regulates the Dot/Icm T4BSS and several additional physiological processes associated with pathogenesis. Because PmrA...
Successful host cell colonization by the Q fever pathogen, Coxiella burnetii, requires translocation of effector proteins into
the host cytosol by a Dot/Icm type 4B secretion system (T4BSS). In Legionella pneumophila, the two-component system (TCS)
PmrAB regulates the Dot/Icm T4BSS and several additional physiological processes associated with pathogenesis. Because PmrA...
Full Text:
Colonization of Mammalian Host Cells
Paul A. Beare,a Kelsi M. Sandoz,a Charles L. Larson,a Dale Howe,a Brent