In recent years, the methyl erythritol phosphate (MEP) pathway to isoprenoids has been the subject of intensive research. The interest is because isoprenoids have important roles in many cellular processes essential for the survival of several pathogenic organisms, making the inhibition of this pathway an attractive target for the drug...
This dissertation describes studies of isoprenoid biosynthesis in the
phytoflagellate Euglena gracilis. Elucidation of a novel isoprerioid pathway, the 2-Cmethyl-D-erythritol-4-phosphate (MEP) pathway, in addition to the generally known
mevalonate (MVA) pathway, led to extensive exploration of the distribution of both pathways in a variety of organisms. To date, photosynthetic eukaryotes...
The discovery of the methylerythritol phosphate pathway (the MEP pathway) as an alternate pathway for isoprenoid biosynthesis in some organisms including most bacteria, malarial parasites and plants, but not in animals, has stimulated extensive studies in this area. Research has revealed the potential of finding novel antibacterials, antimalarial drugs, and...
The primary purpose of this study was to replicate a study of
Abel and Sahinkaya which investigated the emergence of race and sex
preferences of upper middle socioeconomic status Caucasian
children. This study provided a good match with respect to socioeconomic
status, race, and sex; however, the number of subjects...
The purpose of this study was to investigate the relationship
between specific mother-child interactions and selected aspects of
language development in "disadvantaged" children.
The subjects were 19 preschool children in a summer Head
Start program in Denver, Colorado. Their ages ranged from four
years-nine months to five years-seven months. Eighteen...
The purpose of this paper was to study the relationship of a
high school family life course to post high school problems and
marriage role expectations. The specific objective of the study was
to determine whether or not there is a relationship between participation
in a high school family life...
We consider development of sand ripples in shallow water flows which do not reach an equilibrium height but have a time-varying ripple height that slowly reaches a maximum value and then is quickly destroyed by the fluid. A simple scenario to explain the time periodic behavior of the sand ripples...
We exhibit long-lived resonances in scattering from two-dimensional soft cage potentials comprised of three and four Gaussian peaks. Specific low-energy resonances with very narrow width are shown to correspond to classical multiple-reflection events. These states have much larger probability densities inside the cage than outside and mimic bound states in...