Our ability to assess the continental impacts of woody encroachment remains compromised by the paucity of studies quantifying regional encroachment rates. This knowledge gap is especially apparent when it comes to quantifying the impact of woody encroachment on large-scale carbon dynamics. In this study, we use a combination of aerial...
Using the counterflow virtual impactor, a new instrument for sampling cloud droplets, measurable levels of light-absorbing material were found to exist inside droplets in stratocumulus clouds off the coast of southern California. Eighty percent of the samples of droplet residue material had light absorption coefficients ranging from 6 to 20...
Ebola viruses (EBOV) cause severe disease in humans and nonhuman primates with high mortality rates and continue to emerge in new geographic locations, including several countries in West Africa, the site of a large ongoing outbreak. Phosphorodiamidate morpholino oligomers (PMOs) are synthetic antisense molecules that are able to target mRNAs...
Estimation of belowground carbon stocks in tropical wetland forests requires funding for laboratory analyses and suitable facilities, which are often lacking in developing nations where most tropical wetlands are found. It is therefore beneficial to develop simple analytical tools to assist belowground carbon estimation where financial and technical limitations are...
The volume and complexity of their vascular systems make the dynamics of long‐distance water transport in large trees difficult to study. We used heat and deuterated water (D₂O) as tracers to characterize whole‐tree water transport and storage properties in individual trees belonging to the coniferous species Pseudotsuga menziesii (Mirb.) Franco...
Published April 1964. Facts and recommendations in this publication may no longer be valid. Please look for up-to-date information in the OSU Extension Catalog: http://extension.oregonstate.edu/catalog
Published April 1968. Facts and recommendations in this publication may no longer be valid. Please look for up-to-date information in the OSU Extension Catalog: http://extension.oregonstate.edu/catalog
BACKGROUND:
AVI-7288 is a phosphorodiamidate morpholino oligomer with positive charges that targets the viral messenger RNA that encodes Marburg virus (MARV) nucleoprotein. Its safety in humans is undetermined.
METHODS:
We assessed the efficacy of AVI-7288 in a series of studies involving a lethal challenge with MARV in nonhuman primates. The...