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- Creator:
- Roberts, Blaine R., Lim, Nastasia K. H., McAllum, Erin J., Donnelly, Paul S., Hare, Dominic J., Doble, Philip A., Turner, Bradley J., Price, Katherine A., Lim, Sin Chun, Paterson, Brett M., Hickey, James L., Rhoads, Timothy W., Williams, Jared R., Kanninen, Katja M., Hung, Lin W., Liddell, Jeffrey R., Grubman, Alexandra, Monty, Jean-Francois, Llanos, Roxana M., Kramer, David R., Mercer, Julian F. B., Bush, Ashley I., Masters, Colin L., Duce, James A., Li, Qiao-Xin, Beckman, Joseph S., Barnham, Kevin J., White, Anthony R., and Crouch, Peter J.
- Abstract:
- Mutations in the metallo-protein Cu/Zn-superoxide dismutase (SOD1) cause amyotrophic lateral sclerosis (ALS) in humans and an expression level-dependent phenotype in transgenic rodents. We show that oral treatment with the therapeutic agent diacetyl-bis(4-methylthiosemicarbazonato)copper[superscript II] [Cu[superscript II](atsm)] increased the concentration of mutant SOD1 (SOD1G37R) in ALS model mice, but paradoxically improved locomotor...
- Resource Type:
- Article
- Full Text:
- Amyotrophic Lateral Sclerosis Roberts, B. R., Lim, N. K. H., McAllum, E. J., Donnelly, P. S., Hare, D. J
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- Creator:
- Hautier, Yann, Seabloom, Eric W., Borer, Elizabeth T., Adler, Peter B., Harpole, W. Stanley, Hillebrand, Helmut, Lind, Eric M., MacDougall, Andrew S., Stevens, Carly J., Bakker, Jonathan D., Buckley, Yvonne M., Chu, Chengjin, Collins, Scott L., Daleo, Pedro, Damschen, Ellen I., Davies, Kendi F., Fay, Philip A., Firn, Jennifer, Gruner, Daniel S., Jin, Virginia L., Klein, Julia A., Knops, Johannes M. H., La Pierre, Kimberly J., Li, Wei, McCulley, Rebecca L., Melbourne, Brett A., Moore, Joslin L., O'Halloran, Lydia R., Prober, Suzanne M., Risch, Anita C., Sankaran, Mahesh, Schuetz, Martin, and Hector, Andy
- Abstract:
- Studies of experimental grassland communities¹⁻⁷ have demonstrated that plant diversity can stabilize productivity through species asynchrony, in which decreases in the biomass of some species are compensated for by increases in others[superscript 1,2]. However, it remains unknown whether these findings are relevant to natural ecosystems, especially those for which species...
- Resource Type:
- Article
- Full Text:
- Hautier, Y., Seabloom, E. W., Borer, E. T., Adler, P. B., Harpole, W. S., Hillebrand, H., ... & Hector, A
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- Creator:
- Loper, Joyce E., Hassan, Karl A., Mavrodi, Dmitri V., Davis, Edward W., II, Lim, Chee Kent, Shaffer, Brenda T., Elbourne, Liam D. H., Stockwell, Virginia O., Hartney, Sierra L., Breakwell, Katy, Henkels, Marcella D., Tetu, Sasha G., Rangel, Lorena I., Kidarsa, Teresa A., Wilson, Neil L., van de Mortel, Judith E., Song, Chunxu, Blumhagen, Rachel, Radune, Diana, Hostetler, Jessica B., Brinkac, Lauren M., Durkin, A. Scott, Kluepfel, Daniel A., Wechter, W. Patrick, Anderson, Anne J., Kim, Young Cheol, Pierson, Leland S., III, Pierson, Elizabeth A., Lindow, Steven E., Kobayashi, Donald Y., Raaijmakers, Jos M., Weller, David M., Thomashow, Linda S., Allen, Andrew E., and Paulsen, Ian T.
- Abstract:
- We provide here a comparative genome analysis of ten strains within the Pseudomonas fluorescens group including seven new genomic sequences. These strains exhibit a diverse spectrum of traits involved in biological control and other multitrophic interactions with plants, microbes, and insects. Multilocus sequence analysis placed the strains in three sub-clades,...
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- Article
- Full Text:
- . Shaffer1, Liam D. H. Elbourne3, Virginia O. Stockwell2, Sierra L. Hartney2, Katy Breakwell3, Marcella D
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- Creator:
- Loper, Joyce E., Hassan, Karl A., Mavrodi, Dmitri V., Davis, Edward W., II, Lim, Chee Kent, Shaffer, Brenda T., Elbourne, Liam D. H., Stockwell, Virginia O., Hartney, Sierra L., Breakwell, Katy, Henkels, Marcella D., Tetu, Sasha G., Rangel, Lorena I., Kidarsa, Teresa A., Wilson, Neil L., van de Mortel, Judith E., Song, Chunxu, Blumhagen, Rachel, Radune, Diana, Hostetler, Jessica B., Brinkac, Lauren M., Durkin, A. Scott, Kluepfel, Daniel A., Wechter, W. Patrick, Anderson, Anne J., Kim, Young Cheol, Pierson, Leland S., III, Pierson, Elizabeth A., Lindow, Steven E., Kobayashi, Donald Y., Raaijmakers, Jos M., Weller, David M., Thomashow, Linda S., Allen, Andrew E., and Paulsen, Ian T.
- Abstract:
- We provide here a comparative genome analysis of ten strains within the Pseudomonas fluorescens group including seven new genomic sequences. These strains exhibit a diverse spectrum of traits involved in biological control and other multitrophic interactions with plants, microbes, and insects. Multilocus sequence analysis placed the strains in three sub-clades,...
- Resource Type:
- Article
- Full Text:
- . Shaffer1, Liam D. H. Elbourne3, Virginia O. Stockwell2, Sierra L. Hartney2, Katy Breakwell3, Marcella D
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- Creator:
- United States. Agricultural Research Service, Oregon State University. Department of Crop Science, Young, William C. III, Butler, M. D., Simmons, R. B., Weber, J. M., Ball, Daniel A. (Daniel Allen), 1954-, Anderson, N. P., Mellbye, M. E., Silberstein, T. B., Walenta, D. L., Chastain, T. G., Corkery, A. R., Curtis, D. W., Fisher, G. C., Garbacik, C. J., Hulting, A. G., Mallory-Smith, C. A., Rao, S., Roerig, K. C., Clough, G. H., Hamm, P. B., Alderman, S. C., Roerig, G. M., Griffith, S. M., Mueller-Warrant, G. W., Whittaker, G. W., Darris, D. C., and Young-Mathews, A.
- Resource Type:
- Technical Report
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- Creator:
- Buizert, Christo, Adrian, Betty, Ahn, Jinho, Albert, Mary, Alley, Richard B., Baggenstos, Daniel, Bauska, Thomas K., Bay, Ryan C., Bencivengo, Brian B., Bentley, Charles R., Brook, Edward J., Chellman, Nathan J., Clow, Gary D., Cole-Dai, Jihong, Conway, Howard, Cravens, Eric, Cuffey, Kurt M., Dunbar, Nelia W., Edwards, Jon S., Fegyveresi, John M., Ferris, Dave G., Fitzpatrick, Joan J., Fudge, T. J., Gibson, Chris J., Gkinis, Vasileios, Goetz, Joshua J., Gregory, Stephanie, Hargreaves, Geoffrey M., Iverson, Nels, Johnson, Jay A., Jones, Tyler R., Kalk, Michael L., Kippenhan, Matthew J., Koffman, Bess G., Kreutz, Karl, Kuhl, Tanner W., Lebar, Donald A., Lee, James E., Marcott, Shaun A., Markle, Bradley R., Maselli, Olivia J., McConnell, Joseph R., McGwire, Kenneth C., Mitchell, Logan E., Mortensen, Nicolai B., Neff, Peter D., Nishiizumi, Kunihiko, Nunn, Richard M., Orsi, Anais J., Pasteris, Daniel R., Pedro, Joel B., Pettit, Erin C., Price, P. Buford, Priscu, John C., Rhodes, Rachael H., Rosen, Julia L., Schauer, Andrew J., Schoenemann, Spruce W., Sendelbach, Paul J., Severinghaus, Jeffrey P., Shturmakov, Alexander J., Sigl, Michael, Slawny, Kristina R., Souney, Joseph M., Sowers, Todd A., Spencer, Matthew K., Steig, Eric J., Taylor, Kendrick C., Twickler, Mark S., Vaughn, Bruce H., Voigt, Donald E., Waddington, Edwin D., Welten, Kees C., Wendricks, Anthony W., White, James W. C., Winstrup, Mai, Wong, Gifford J., and Woodruff, Thomas E.
- Abstract:
- The last glacial period exhibited abrupt Dansgaard–Oeschger climatic oscillations, evidence of which is preserved in a variety of Northern Hemisphere palaeoclimate archives¹. Ice cores show that Antarctica cooled during the warm phases of the Greenland Dansgaard–Oeschger cycle and vice versa[superscript 2,3], suggesting an interhemispheric redistribution of heat through a mechanism...
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- Article
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- –38 N G R IP δ 18 O (‰ ) 350 400 450 500 550 600 650 W D C C H 4 (p .p .b .) –42
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- Creator:
- Alford, Matthew H., Peacock, Thomas, MacKinnon, Jennifer A., Nash, Jonathan D., Buijsman, Maarten C., Centurioni, Luca R., Chao, Shenn-Yu, Chang, Ming-Huei, Farmer, David M., Fringer, Oliver B., Fu, Ke-Hsien, Gallacher, Patrick C., Graber, Hans C., Helfrich, Karl R., Jachec, Steven M., Jackson, Christopher R., Klymak, Jody M., Ko, Dong S., Jan, Sen, Johnston, T. M. Shaun, Legg, Sonya, Lee, I-Huan, Lien, Ren-Chieh, Mercier, Matthieu J., Moum, James N., Musgrave, Ruth, Park, Jae-Hun, Pickering, Andrew I., Pinkel, Robert, Rainville, Luc, Ramp, Steven R., Rudnick, Daniel L., Sarkar, Sutanu, Scotti, Alberto, Simmons, Harper L., St. Laurent, Louis C., Venayagamoorthy, Subhas K., Wang, Yu-Huai, Wang, Joe, Yang, Yiing J., Paluszkiewicz, Theresa, and Tang, Tswen-Yung (David)
- Abstract:
- Internal gravity waves, the subsurface analogue of the familiar surface gravity waves that break on beaches, are ubiquitous in the ocean. Because of their strong vertical and horizontal currents, and the turbulent mixing caused by their breaking, they affect a panoply of ocean processes, such as the supply of nutrients...
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- Article
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- China Sea The formation and fate of internal waves in the South China Sea Alford, M. H., Peacock, T
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- Creator:
- Ciais, P., Dolman, A. J., Bombelli, A., Duren, R., Peregon, A., Rayner, P. J., Miller, C., Gobron, N., Kinderman, G., Marland, G., Gruber, N., Chevallier, F., Andres, R. J., Balsamo, G., Bopp, L., Bréon, F.-M., Broquet, G., Dargaville, R., Battin, T. J., Borges, A., Bovensmann, H., Buchwitz, M., Butler, J., Canadell, J. G., Cook, R. B., DeFries, R., Engelen, R., Gurney, K. R., Heinze, C., Heimann, M., Held, A., Henry, M., Law, B., Luyssaert, S., Miller, J., Moriyama, T., Moulin, C., Myneni, R. B., Nussli, C., Obersteiner, M., Ojima, D., Pan, Y., Paris, J.-D., Piao, S. L., Poulter, B., Plummer, S., Quegan, S., Raymond, P., Reichstein, M., Rivier, L., Sabine, C., Schimel, D., Tarasova, O., Valentini, R>, Wang, R., van der Werf, G., Wickland, D., Williams, M., and Zehner, C.
- Abstract:
- A globally integrated carbon observation and analysis system is needed to improve the fundamental understanding of the global carbon cycle, to improve our ability to project future changes, and to verify the effectiveness of policies aiming to reduce greenhouse gas emissions and increase carbon sequestration. Building an integrated carbon observation...
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- Article
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- . Dargaville5, T. J. Battin12, A. Borges13, H. Bovensmann14, M. Buchwitz14, J. Butler15, J. G. Canadell16, R. B
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- Creator:
- Blake, D. F., Morris, R. V., Kocurek, G., Morrison, S. M., Downs, R. T., Bish, D., Ming, D. W., Edgett, K. S., Rubin, D., Goetz, W., Madsen, M. B., Sullivan, R., Gellert, R., Campbell, I., Treiman, A. H., McLennan, S. M., Yen, A. S., Grotzinger, J., Vaniman, D. T., Chipera, S. J., Achilles, C. N., Rampe, E. B., Sumner, D., Meslin, P.-Y., Maurice, S., Forni, O., Gasnault, O., Fisk, M., Schmidt, M., Mahaffy, P., Leshin, L. A., Glavin, D., Steele, A., Freissinet, C., Navarro-González, R., Yingst, R. A., Kah, L. C., Bridges, N., Lewis, K. W., Bristow, T. F., Farmer, J. D., Crisp, J. A., Stolper, E. M., Des Marais, D. J., Sarrazin, P., and MSL Science Team
- Abstract:
- The Rocknest aeolian deposit is similar to aeolian features analyzed by the Mars Exploration Rovers (MERs) Spirit and Opportunity. The fraction of sand <150 micrometers in size contains ~55% crystalline material consistent with a basaltic heritage and ~45% x-ray amorphous material. The amorphous component of Rocknest is iron-rich and silicon-poor...
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- Article
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- I. Campbell,11 A. H. Treiman,12 S. M. McLennan,13 A. S. Yen,14 J. Grotzinger,15 D. T. Vaniman,16 S
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- Creator:
- Seabloom, Eric W., Borer, Elizabeth T., Buckley, Yvonne, Cleland, Elsa E., Davies, Kendi, Firn, Jennifer, Harpole, W. Stanley, Hautier, Yann, Lind, Eric, Macdougall, Andrew, Orrock, John L., Prober, Suzanne M., Adler, Peter, Alberti, Juan, Anderson, T. Michael, Bakker, Jonathan D., Biederman, Lori A., Blumenthal, Dana, Brown, Cynthia S., Brudvig, Lars A., Caldeira, Maria, Chu, Chengjin, Crawley, Michael J., Daleo, Pedro, Damschen, Ellen I., D'Antonio, Carla M., Decrappeo, Nicole M., Dickman, Chris R., Du, Guozhen, Fay, Philip A., Frater, Paul, Gruner, Daniel S., Hagenah, Nicole, Hector, Andrew, Helm, Aveliina, Hillebrand, Helmut, Hofmockel, Kirsten S., Humphries, Hope C., Iribarne, Oscar, Jin, Virginia L., Kay, Adam, Kirkman, Kevin P., Klein, Julia A., Knops, Johannes M. H., La Pierre, Kimberly J., Ladwig, Laura M., Lambrinos, John G., Leakey, Andrew D. B., Li, Qi, Li, Wei, Mcculley, Rebecca, Melbourne, Brett, Mitchell, Charles E., Moore, Joslin L., Morgan, John, Mortensen, Brent, O'Halloran, Lydia R., Paertel, Meelis, Pascual, Jesus, Pyke, David A., Risch, Anita C., Salguero-Gomez, Roberto, Sankaran, Mahesh, Schuetz, Martin, Simonsen, Anna, Smith, Melinda, Stevens, Carly, Sullivan, Lauren, Wardle, Glenda M., Wolkovich, Elizabeth M., Wragg, Peter D., Wright, Justin, and Yang, Louie
- Abstract:
- Invasions have increased the size of regional species pools, but are typically assumed to reduce native diversity. However, global-scale tests of this assumption have been elusive because of the focus on exotic species richness, rather than relative abundance. This is problematic because low invader richness can indicate invasion resistance by...
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- X X Kevin P Kirkman X X Julia A. Klein X X Johannes M. H. Knops X X