Liquid transportation fuels require costly and time-consuming tests to characterize metrics, such as Research Octane Number (RON) for gasoline. If fuel sale restrictions requiring use of standard Cooperative Fuel Research (CFR) testing procedures do not apply, these tests may be avoided by using multivariate statistical models to predict RON and...
Heavy chronic alcohol consumption has been linked to a myriad of
detrimental skeletal effects. Many studies have been conducted to examine
the effects of alcohol abuse upon cancellous bone. However, little is known
about its effect upon cortical bone. The skeleton is comprised of
approximately 80% cortical bone and thus...
A critical component in diabetes management is diabetes self-management education (DSME). Additionally, poor self-management behavior and negative health outcomes are associated with participants that do not complete diabetes education (Gurdiacci et al., 2007). Despite the widespread use of DSME, many do not obtain the wide range of benefits these programs...
This dissertation explores one overarching question relevant to the
paleoclimate of the latest Pleistocene glacial cycle (approximately the last
130,000 years): “How did spatial and temporal evolution of ocean
temperature, both at the surface and interior, relate to other parts of the
climate system in the late Pleistocene?” Results from...
Polycentric networks of formal organizations and informal stakeholder groups, as opposed to centralized institutional hierarchies, can be critically important for strengthening the capacity of governance systems to adapt to unexpected social and biophysical change. Adaptive governance is one type of environmental governance characterized by the emergence of networks that stimulate...
An Expert Panel convened by the National Lipid Association previously developed a consensus set of recommendations for the patient-centered management of dyslipidemia in clinical medicine (part 1). These were guided by the principle that reducing elevated levels of atherogenic cholesterol (non–high-density lipoprotein cholesterol and low-density lipoprotein cholesterol) reduces the risk...
Full Text:
: Part 2’’ James A. Underberg,
DOI of original article: http://dx.doi.org/10.1016/j.jacl.2015.09.002
The immobilization of chelators to solid supports has recently gained renewed interest due to the increasing biomedical and environmental applications made possible by these molecules’ ability to bind Fe(III) and other metal ions. The uses of immobilized chelators have expanded to include the treatment of metal overload in serum, the...
TAC is the most commonly used medication in post transplantation maintenance immunosuppression therapy. TAC lipophilicity and its erratic oral absorption especially in the presence of food intake result in great intra- and interpatient pharmacokinetic variations. Complicated dosing and frequent required therapeutic monitoring is thought to be the main cause of...
Alcohol is a widely consumed, nonessential, bioactive nutrient with end-organ effects on the skeleton. Moderate levels of alcohol consumption are generally associated with increased bone mineral density (BMD), whereas higher intake levels result in reduced bone formation, bone loss, and increased risk for osteoporotic fracture. Given the negative impact of...
Sugar phosphate cyclases (SPCs) are enzymes involved in the biosynthesis of many important natural products. SPCs form a unique cyclitol during the early steps in the biosynthesis of many natural products. These natural products include rifamycin, which is chemically modified to rifampicin and used clinically as an antituberculosis drug, and...