Positively-charged gold nanoparticles (0.8-nm core diameter) reduced yeast
survival, but not growth, at a concentration of 10 to 100 μg/ml. Among 17 resistant
deletion mutants isolated in a genome-wide screen, highly significant enrichment
was observed for respiration-deficient mutants lacking genes encoding proteins
associated with the mitochondrion.
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cerevisiae Suggests a Role for Respiratory Metabolism
in Mediating Toxicity
MarkR. Smith,a Matthew G
Positively-charged gold nanoparticles (0.8-nm core diameter) reduced yeast
survival, but not growth, at a concentration of 10 to 100 μg/ml. Among 17 resistant
deletion mutants isolated in a genome-wide screen, highly significant enrichment
was observed for respiration-deficient mutants lacking genes encoding proteins
associated with the mitochondrion.
Positively-charged gold nanoparticles (0.8-nm core diameter) reduced yeast
survival, but not growth, at a concentration of 10 to 100 μg/ml. Among 17 resistant
deletion mutants isolated in a genome-wide screen, highly significant enrichment
was observed for respiration-deficient mutants lacking genes encoding proteins
associated with the mitochondrion.
Wood is a major pool of organic carbon that is highly resistant to decay, owing largely to the presence of lignin. The only organisms capable of substantial lignin decay are white rot fungi in the Agaricomycetes, which also contains non–lignin-degrading brown rot and ectomycorrhizal species. Comparative analyses of 31 fungal...
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analyzed with BISSE in the R package Diversitree (56) on the same ultrametric Bayesian tree
sample used
Plants possess two myosin classes, VIII and XI. The myosins XI are implicated in organelle transport, filamentous actin
organization, and cell and plant growth. Due to the large size of myosin gene families, knowledge of these molecular motors
remains patchy. Using deep transcriptome sequencing and bioinformatics, we systematically investigated myosin...
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mark alternative splicing events. B, Brachypodium XI-K
ortholog (Bradi2g41980). A box denotes novel
We studied the natural hybrid (Fragaria ×ananassa subsp. cuneifolia) between
two sexually dimorphic octoploid strawberry species (F. virginiana and F.
chiloensis) to gain insight into the dynamics of sex chromosomes and the
genesis of sexual dimorphism. Male sterility is dominant in both the parental
species and thus will be inherited...
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authors declare no conflict of interest. 662
Acknowledgements 663
We thank R. Dalton, D. Jackson, B
Although a large number of single nucleotide polymorphism (SNP) markers covering the entire genome are needed to enable molecular breeding efforts such as genome wide association studies, fine mapping, genomic selection and marker-assisted selection in peach [Prunus persica (L.) Batsch] and related Prunus species, only a limited number of genetic...
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Micheletti6, Umesh R. Rosyara7, Federica Cattonaro3, Elisa Vendramin1,
Dorrie Main8, Valeria Aramini1, Andrea
In the Pacific Northwest snow is an important
natural resource. The inability to accurately measure or
monitor this resource throughout remote areas is a hindrance
to water management. ERTS-1 imagery provides the capability
for extracting a significant amount of scientific information
and data regarding snow conditions in accessible and inaccessible...
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Identification of new molecular targets for the treatment of breast cancer is an important clinical goal, especially for triple-negative breast cancer, which is refractory to existing targeted treatments. The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor known primarily as the mediator of dioxin toxicity. However, the AhR can...
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for technical assistance, Sam Bradford for
excellent flow cytometry assistance, Drs Mark Leid, Nancy