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- Creator:
- Roberts, Blaine R., Lim, Nastasia K. H., McAllum, Erin J., Donnelly, Paul S., Hare, Dominic J., Doble, Philip A., Turner, Bradley J., Price, Katherine A., Lim, Sin Chun, Paterson, Brett M., Hickey, James L., Rhoads, Timothy W., Williams, Jared R., Kanninen, Katja M., Hung, Lin W., Liddell, Jeffrey R., Grubman, Alexandra, Monty, Jean-Francois, Llanos, Roxana M., Kramer, David R., Mercer, Julian F. B., Bush, Ashley I., Masters, Colin L., Duce, James A., Li, Qiao-Xin, Beckman, Joseph S., Barnham, Kevin J., White, Anthony R., and Crouch, Peter J.
- Abstract:
- Mutations in the metallo-protein Cu/Zn-superoxide dismutase (SOD1) cause amyotrophic lateral sclerosis (ALS) in humans and an expression level-dependent phenotype in transgenic rodents. We show that oral treatment with the therapeutic agent diacetyl-bis(4-methylthiosemicarbazonato)copper[superscript II] [Cu[superscript II](atsm)] increased the concentration of mutant SOD1 (SOD1G37R) in ALS model mice, but paradoxically improved locomotor...
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- Article
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- ,3,4 Dominic J. Hare,1,6 Philip A. Doble,6 Bradley J. Turner,1 Katherine A. Price,2 Sin Chun Lim,3,4
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- Creator:
- Jordan, Tuajuanda C., Burnett, Sandra H., Carson, Susan, Caruso, Steven M., Clase, Kari, DeJong, Randall J., Dennehy, John J., Denver, Dee R., Dunbar, David, Elgin, Sarah C. R., Findley, Ann M., Gissendanner, Chris R., Golebiewska, Urszula P., Guild, Nancy, Hartzog, Grant A., Grillo, Wendy H., Hollowell, Gail P., Hughes, Lee E., Johnson, Allison, King, Rodney A., Lewis, Lynn O., Li, Wei, Rosenzweig, Frank, Rubin, Michael R., Saha, Margaret S., Sandoz, James, Shaffer, Christopher D., Taylor, Barbara, Temple, Louise, Vazquez, Edwin, Ware, Vassie C., Barker, Lucia P., Bradley, Kevin W., Jacobs-Sera, Deborah, Pope, Welkin H., Russell, Daniel A., Cresawn, Steven G., Lopatto, David, Bailey, Cheryl P., and Hatfull, Graham F.
- Abstract:
- Engaging large numbers of undergraduates in authentic scientific discovery is desirable but difficult to achieve. We have developed a general model in which faculty and teaching assistants from diverse academic institutions are trained to teach a research course for first-year undergraduate students focused on bacteriophage discovery and genomics. The course...
- Full Text:
- ., Carson, S., Caruso, S. M., Clase, K., DeJong, R. J., ... & Hatfull, G. F. (2014). A Broadly
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- Creator:
- Jordan, Tuajuanda C., Burnett, Sandra H., Carson, Susan, Caruso, Steven M., Clase, Kari, DeJong, Randall J., Dennehy, John J., Denver, Dee R., Dunbar, David, Elgin, Sarah C. R., Findley, Ann M., Gissendanner, Chris R., Golebiewska, Urszula P., Guild, Nancy, Hartzog, Grant A., Grillo, Wendy H., Hollowell, Gail P., Hughes, Lee E., Johnson, Allison, King, Rodney A., Lewis, Lynn O., Li, Wei, Rosenzweig, Frank, Rubin, Michael R., Saha, Margaret S., Sandoz, James, Shaffer, Christopher D., Taylor, Barbara, Temple, Louise, Vazquez, Edwin, Ware, Vassie C., Barker, Lucia P., Bradley, Kevin W., Jacobs-Sera, Deborah, Pope, Welkin H., Russell, Daniel A., Cresawn, Steven G., Lopatto, David, Bailey, Cheryl P., and Hatfull, Graham F.
- Abstract:
- Engaging large numbers of undergraduates in authentic scientific discovery is desirable but difficult to achieve. We have developed a general model in which faculty and teaching assistants from diverse academic institutions are trained to teach a research course for first-year undergraduate students focused on bacteriophage discovery and genomics. The course...
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- Creator:
- Jordan, Tuajuanda C., Burnett, Sandra H., Carson, Susan, Caruso, Steven M., Clase, Kari, DeJong, Randall J., Dennehy, John J., Denver, Dee R., Dunbar, David, Elgin, Sarah C. R., Findley, Ann M., Gissendanner, Chris R., Golebiewska, Urszula P., Guild, Nancy, Hartzog, Grant A., Grillo, Wendy H., Hollowell, Gail P., Hughes, Lee E., Johnson, Allison, King, Rodney A., Lewis, Lynn O., Li, Wei, Rosenzweig, Frank, Rubin, Michael R., Saha, Margaret S., Sandoz, James, Shaffer, Christopher D., Taylor, Barbara, Temple, Louise, Vazquez, Edwin, Ware, Vassie C., Barker, Lucia P., Bradley, Kevin W., Jacobs-Sera, Deborah, Pope, Welkin H., Russell, Daniel A., Cresawn, Steven G., Lopatto, David, Bailey, Cheryl P., and Hatfull, Graham F.
- Abstract:
- Engaging large numbers of undergraduates in authentic scientific discovery is desirable but difficult to achieve. We have developed a general model in which faculty and teaching assistants from diverse academic institutions are trained to teach a research course for first-year undergraduate students focused on bacteriophage discovery and genomics. The course...
- Resource Type:
- Article
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- Creator:
- Fudge, T. J., Steig, Eric J., Markle, Bradley R., Schoenemann, Spruce W., Ding, Qinghua, Taylor, Kendrick C., McConnell, Joseph R., Brook, Edward J., Sowers, Todd, White, James W. C., Alley, Richard B., Cheng, Hai, Clow, Gary D., Cole-Dai, Jihong, Conway, Howard, Cuffey, Kurt M., Edwards, Jon S., Edwards, R. Lawrence, Edwards, Ross, Fegyveresi, John M., Ferris, David, Fitzpatrick, Joan J., Johnson, Jay, Hargreaves, Geoffrey, Lee, James E., Maselli, Olivia J., Mason, William, McGwire, Kenneth C., Mitchell, Logan E., Mortensen, Nicolai, Neff, Peter, Orsi, Anais J., Popp, Trevor J., and Schauer, Andrew J.
- Abstract:
- The cause of warming in the Southern Hemisphere during the most recent deglaciation remains a matter of debate[superscript 1,2]. Hypotheses for a Northern Hemisphere trigger, through oceanic redistributions of heat, are based in part on the abrupt onset of warming seen in East Antarctic ice cores and dated to 18,000...
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- Article
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- –400 δD (‰ ) C O 2 (p .p .m .) O p al fl ux (g c m –2 k yr –1 ) 0.07 0.08 0.09
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- Creator:
- Bjorkstedt, Eric P., Goericke, Ralf, McClatchie, Sam, Weber, Ed, Watson, William, Lo, Nancy, Peterson, William T., Brodeur, Richard D., Auth, Toby, Fisher, Jennifer, Morgan, Cheryl, Peterson, Jay, Largier, John, Bograd, Steven J., Durazo, Reginaldo, Gaxiola-Castro, Gilberto, Lavaniegos, Bertha, Chavez, Francisco P., Collins, Curtis A., Hannah, Bob, Field, John, Sakuma, Keith, Satterthwaite, Will, O'Farrell, Michael, Hayes, Sean, Harding, Jeff, Sydeman, William J., Thompson, Sarah Ann, Warzybok, Pete, Bradley, Russell, Jahncke, Jaime, Golightly, Richard T., Schneider, Stephanie R., Suryan, Robert M., Gladics, Amanda J., Horton, Cheryl A., Kim, Sung Yong, Melin, Sharon R., DeLong, Robert L., and Abell, Jeffrey
- Abstract:
- The state of the California Current System (CCS) since spring 2011 has evolved in response to dissipation of La Niña through spring and summer, resurgence of cooler La Niña conditions in fall and winter, and finally a transition towards ENSO-neutral conditions in spring 2012. The resurgence of La Niña was...
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- Article
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- Petaluma, cA 94952 PEtE WArzyBok, rUssEll BrAdlEy, jAiME jAHNckE PrBo conservation science 3820
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- Creator:
- Buizert, Christo, Adrian, Betty, Ahn, Jinho, Albert, Mary, Alley, Richard B., Baggenstos, Daniel, Bauska, Thomas K., Bay, Ryan C., Bencivengo, Brian B., Bentley, Charles R., Brook, Edward J., Chellman, Nathan J., Clow, Gary D., Cole-Dai, Jihong, Conway, Howard, Cravens, Eric, Cuffey, Kurt M., Dunbar, Nelia W., Edwards, Jon S., Fegyveresi, John M., Ferris, Dave G., Fitzpatrick, Joan J., Fudge, T. J., Gibson, Chris J., Gkinis, Vasileios, Goetz, Joshua J., Gregory, Stephanie, Hargreaves, Geoffrey M., Iverson, Nels, Johnson, Jay A., Jones, Tyler R., Kalk, Michael L., Kippenhan, Matthew J., Koffman, Bess G., Kreutz, Karl, Kuhl, Tanner W., Lebar, Donald A., Lee, James E., Marcott, Shaun A., Markle, Bradley R., Maselli, Olivia J., McConnell, Joseph R., McGwire, Kenneth C., Mitchell, Logan E., Mortensen, Nicolai B., Neff, Peter D., Nishiizumi, Kunihiko, Nunn, Richard M., Orsi, Anais J., Pasteris, Daniel R., Pedro, Joel B., Pettit, Erin C., Price, P. Buford, Priscu, John C., Rhodes, Rachael H., Rosen, Julia L., Schauer, Andrew J., Schoenemann, Spruce W., Sendelbach, Paul J., Severinghaus, Jeffrey P., Shturmakov, Alexander J., Sigl, Michael, Slawny, Kristina R., Souney, Joseph M., Sowers, Todd A., Spencer, Matthew K., Steig, Eric J., Taylor, Kendrick C., Twickler, Mark S., Vaughn, Bruce H., Voigt, Donald E., Waddington, Edwin D., Welten, Kees C., Wendricks, Anthony W., White, James W. C., Winstrup, Mai, Wong, Gifford J., and Woodruff, Thomas E.
- Abstract:
- The last glacial period exhibited abrupt Dansgaard–Oeschger climatic oscillations, evidence of which is preserved in a variety of Northern Hemisphere palaeoclimate archives¹. Ice cores show that Antarctica cooled during the warm phases of the Greenland Dansgaard–Oeschger cycle and vice versa[superscript 2,3], suggesting an interhemispheric redistribution of heat through a mechanism...
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- Article
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- change during the last ice age Buizert, C., Adrian, B., Ahn, J., Albert, M., Alley, R. B., Baggenstos
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- Creator:
- Pfeifer, Marion, Lefebvre, Veronique, Gardner, Toby A., Arroyo‐Rodriguez, Victor, Baeten, Lander, Banks‐Leite, Cristina, Barlow, Jos, Betts, Matthew G., Brunet, Joerg, Cerezo, Alexis, Cisneros, Laura M., Collard, Stuart, D'Cruze, Neil, da Silva Motta, Catarina, Duguay, Stephanie, Eggermont, Hilde, Eigenbrod, Felix, Hadley, Adam S., Hanson, Thor R., Hawes, Joseph E., Heartsill Scalley, Tamara, Klingbeil, Brian T., Kolb, Annette, Kormann, Urs, Kumar, Sunil, Lachat, Thibault, Lakeman Fraser, Poppy, Lantschner, Victoria, Laurance, William F., Leal, Inara R., Lens, Luc, Marsh, Charles J., Medina‐Rangel, Guido F., Melles, Stephanie, Mezger, Dirk, Oldekop, Johan A., Overal, William L., Owen, Charlotte, Peres, Carlos A., Phalan, Ben, Pidgeon, Anna M., Pilia, Oriana, Possingham, Hugh P., Possingham, Max L., Raheem, Dinarzarde C., Ribeiro, Danilo B., Ribeiro Neto, Jose D., Robinson, W. Douglas, Robinson, Richard, Rytwinski, Trina, Scherber, Christoph, Slade, Eleanor M., Somarriba, Eduardo, Stouffer, Philip C., Struebig, Matthew J., Tylianakis, Jason M., Tscharntke, Teja, Tyre, Andrew J., Urbina Cardona, Jose N., Vasconcelos, Heraldo L., Wearn, Oliver, Wells, Konstans, Willig, Michael R., Wood, Eric, Young, Richard P., Bradley, Andrew V., and Ewers, Robert M.
- Abstract:
- Habitat fragmentation studies have produced complex results that are challenging to synthesize. Inconsistencies among studies may result from variation in the choice of landscape metrics and response variables, which is often compounded by a lack of key statistical or methodological information. Collating primary datasets on biodiversity responses to fragmentation in...
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- Article
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- FRAGmentation Pfeifer, M., Lefebvre, V., Gardner, T. A., Arroyo‐Rodriguez, V., Baeten, L., Banks‐ Leite, C
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- Creator:
- Wells, Brian K., Schroeder, Isaac D., Santora, Jarrod A., Hazen, Elliott L., Bograd, Steven J., Bjorkstedt, Eric P., Loeb, Valerie J., Mcclatchie, Sam, Weber, Edward D., Watson, William, Thompson, Andrew R., Peterson, William T., Brodeur, Richard D., Harding, Jeff, Field, John, Sakuma, Keith, Hayes, Sean, Mantua, Nathan, Sydeman, William J., Losekoot, Marcel, Thompson, Sarah Ann, Largier, John, Kim, Sung Yong, Chavez, Francisco P., Barceló, Caren, Warzybok, Pete, Bradley, Russel, Jahncke, Jaime, Goericke, Ralf, Campbell, Gregory S., Hildebrand, John A., Melin, Sharon R., Delong, Robert L., Gomez-Valdes, Jose, Lavaniegos, Bertha, Gaxiola-Castro, Gilberto, Golightly, Richard T., Schneider, Stephanie R., Lo, Nancy, Suryan, Robert M., Gladics, Amanda J., Horton, Cheryl A., Fisher, Jennifer, Morgan, Cheryl, Peterson, Jay, Daly, Elizabeth A., Auth, Toby D., and Abell, Jeffrey
- Abstract:
- This report reviews the state of the California Current System (CCS) between winter 2012 and spring 2013, and includes observations from Washington State to Baja California. During 2012, large-scale climate modes indicated the CCS remained in a cool, productive phase present since 2007. The upwelling season was delayed north of...
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- , OR 97331-5503 PETE WARZYBOK, RUSSEL BRADLEY, JAIME JAHNCKE PRBO Conservation Science 3820 Cypress
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- Creator:
- Wells, Brian K., Schroeder, Isaac D., Santora, Jarrod A., Hazen, Elliott L., Bograd, Steven J., Bjorkstedt, Eric P., Loeb, Valerie J., Mcclatchie, Sam, Weber, Edward D., Watson, William, Thompson, Andrew R., Peterson, William T., Brodeur, Richard D., Harding, Jeff, Field, John, Sakuma, Keith, Hayes, Sean, Mantua, Nathan, Sydeman, William J., Losekoot, Marcel, Thompson, Sarah Ann, Largier, John, Kim, Sung Yong, Chavez, Francisco P., Barceló, Caren, Warzybok, Pete, Bradley, Russel, Jahncke, Jaime, Goericke, Ralf, Campbell, Gregory S., Hildebrand, John A., Melin, Sharon R., Delong, Robert L., Gomez-Valdes, Jose, Lavaniegos, Bertha, Gaxiola-Castro, Gilberto, Golightly, Richard T., Schneider, Stephanie R., Lo, Nancy, Suryan, Robert M., Gladics, Amanda J., Horton, Cheryl A., Fisher, Jennifer, Morgan, Cheryl, Peterson, Jay, Daly, Elizabeth A., Auth, Toby D., and Abell, Jeffrey
- Abstract:
- This report reviews the state of the California Current System (CCS) between winter 2012 and spring 2013, and includes observations from Washington State to Baja California. During 2012, large-scale climate modes indicated the CCS remained in a cool, productive phase present since 2007. The upwelling season was delayed north of...
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- . Copepod data are based on samples collected with a 0.5 m diameter ring net of 202 µm mesh, hauled from