An approach to understanding and managing anadromous salmon, steelhead,
and sea-run cutthroat trout (Oncorhynchus spp.) based on life history and
evolutionary adaptive capacities of species and stocks is presented. Species, stocks,
and local populations are viewed as systems that are continuously adapting to
changing environmental conditions. They have the potential...
Lymphomas and leukemias are the most common cancer in children and young adults and in utero exposure to carcinogens may contribute to the etiology of these cancers. A polycyclic aromatic hydrocarbon (PAH), dibenzo[a,l]pyrene (DBP), was administered to pregnant mice (15 mg/Kg b.w., gavage) on gestation day 17. Significant mortalities in...
A novel type of model substrates, i.e. immobilized p-aminophenyl-β-D-cellooligosaccharides,
was developed and used in the study of exocellulases. The
two major cellobiohydrolases from Trichoderma reesei, CBH I and CBH II were
used as representative enzymes. p-Aminophenyl derivatives of cellobiose (PAPG₂),
cellotriose (PAPG₃), and cellotetraose (PAPG₄) were synthesized from the reaction...
This research was designed to study the perinatal and
postweaning effects of the interaction between ethanol and low
dietary zinc during gestation and lactation in the rat.
Pregnant rats were fed liquid diets containing either 2 or 10
μg zinc/ml with or without 30% of kcal from ethanol throughout
gestation...
The objectives were to investigate the ability of a two-factor
central composite rotatable design (CCRD), using cooking temperature
(CT) and endpoint temperature (ET) as independent variables, to
predict selected chemical, physical and sensory meat quality
characteristics considered important by the industry, researcher and
consumer alike. Response surface analysis (RSA) was...
Proteolytic degradation of fish flesh occurring at elevated temperatures is the
primary limitation for the commercial utilization of arrowtooth flounder (ATF).
Characterization of the autolytic activity of ATF muscle incubated at various pHs
and temperatures indicated the involvement of heat-activated proteinases active at
acidic and alkaline pHs. Further characterization of...
Dysfunction of mitochondria has been linked to aging and the pathogenesis of many degenerative diseases. Aside from their primary function in energy production, mitochondria are considered as a major source and target of reactive oxygen and nitrogen species (ROS/RNS) in cells as well. The mitochondrial thiol proteome is a subset...
Studies towards the total synthesis of (−)-kendomycin (1), a bacterial metabolite with
a unique molecular architecture and pronounced biological activity, are described. These
studies resulted in the synthesis of advanced intermediate 208, containing all of the
carbon atoms of 1.
A Dötz annulation between alkyne 122 and novel chromium carbenoid...