The anticonvulsant drug carbamazepine (CBZ) is a commonly prescribed drug that is used to treat patients with neurological disorders including epilepsy and bi-polar disorder. CBZ has a narrow range of efficacy: Below the therapeutic dose, seizures and other conditions are not controlled, and above the recommended window, patients experience side...
Intuitively, it seems as though natural language processing tasks might benefit from explicit representations of the syntactic and semantic properties of text. Ontonotes is a dataset which attempts to annotate texts, to represent as much as possible of the meaning of the text explicitly within the annotation. Many tools exist...
Global annual average temperatures are rising, creating extreme heat events or heatwaves that are increasing in frequency, length, and severity. The world will endure more of these events as climate change worsens and heat-related mortality and morbidity will increase due to warming conditions. At the center of heatwaves are urban...
The utility of high-throughput, computational screening has become an invaluable asset to the field of materials science. In the hierarchy of computational methods, the most accurate methods are often the most computationally expensive. However, as both the efficiency and fidelity of numerical techniques advance, high-quality screening of large materials datasets...
Learning to recognize objects is a fundamental and essential step in human perception and understanding of the world. Accordingly, research of object discovery across diverse modalities plays a pivotal role in the context of computer vision. This field not only contributes significantly to enhancing our understanding of visual information but...
Cell signaling under external stimulation is a critical mechanism that governs many biological processes such as cell proliferation, cell migration, and cell apoptosis, etc. For multicellular organisms, the ability to synchronize heterogeneous individual cellular responses through intercellular communication is crucial to maintain normal functionality. However, even though the biological pathways...
Excavations at the Cooper’s Ferry site (10IH73) revealed a long record of repeated human occupation extending from the late Pleistocene into the early Holocene (~16,000-10,000 cal BP) and have yielded unique insights into the Western Stemmed Tradition (WST), which includes. Several studies have focused on WST pit features encountered at...
Background: We present a model for reporting accelerometer paradata (process-related data produced from survey administration) collected in the International Study of Childhood Obesity Lifestyle and the Environment (ISCOLE), a multi-national investigation of >7000 children (averaging 10.5 years of age) sampled from 12 different developed and developing countries and five continents....
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-Locke, C., Mire, E. F., Dentro, K. N., Barreira, T. V., Schuna, J. M., Zhao,
P., ... & Katzmarzyk, P. T
Fungal hyphae are among the most highly polarized cells. Hyphal polarized
growth is supported by tip-directed transport of secretory vesicles, which accumulate temporarily
in a stratified manner in an apical vesicle cluster, the Spitzenkörper. The exocyst complex
is required for tethering of secretory vesicles to the apical plasma membrane. We...
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Riquelmea, Erin L. Bredewegb,*, Olga Callejas-Negretea,*, Robert W. Robersonc,
Sarah Ludwigd, Alejandro