The Emigrant Pass volcanics (EPV) are a 38.3 to 36.4 Ma calc-alkaline volcanic center that erupted andesite and dacite, and a late series of felsic dikes along the south flank of the Carlin gold district in north-central Nevada. The EPV includes dacite and rhyolite porphyry dikes indistinguishable from porphyry dikes...
More than 30 members of the diverse amphidinolide family of biologically active macrolides have been isolated over last three decades. From this family, amphidinolides C and F stand among the most complex and densely functionalized affiliates. Recently, we have accomplished the first total synthesis of amphidinolide F. The all-carbon framework...
This dissertation is concerned with the behavior of sulfur in intermediate-silicic arc magmas associated with subduction at convergent margins. In particular it focusses on oxidized, sulfur-rich magmas, the conditions at which they might reach sulfate saturation, and implications of sulfate saturation. It is divided into an investigation of natural samples...
Cell signaling under external stimulation is a critical mechanism that governs many biological processes such as cell proliferation, cell migration, and cell apoptosis, etc. For multicellular organisms, the ability to synchronize heterogeneous individual cellular responses through intercellular communication is crucial to maintain normal functionality. However, even though the biological pathways...
Improving crop cultivars for use on organic farms is pertinent, as current elite germplasm is less resilient within the more variable context of organic farm environments. Although a growing number of studies have focused on organic plant breeding in cereal crops, very few have focused on vegetable crops, especially those...
Animals aggregate and interact in nonuniform and nonrandom patterns, which lead to group level characteristics that have important evolutionary and ecological consequences. Network analysis provides a useful conceptual framework for linking animal interactions at all scales from dyads to communities, to populations and ecosystems. Despite exciting theoretical and applied advances...
In this dissertation, the structure and electronic properties of multiple metal oxide thin films are characterized and presented. Prompt inorganic condensation (PIC) of metal-oxo and –hydroxo clusters was evaluated as a technique for making metal oxide clusters in two separate studies. The first focuses on the synthesis of lithium niobate...
Human liver cancer is one of the deadliest cancers worldwide, with hepatocellular carcinoma (HCC) being the most common type. Aberrant Ras signaling has been implicated in the development and progression of human HCC, but a complete understanding of the molecular mechanisms of this protein in hepatocarcinogenesis remains elusive. In this...
This thesis is composed of four parts: i) system
description, ii) model development, iii) parameter
estimation, and iv) validation. The natural system used
here is an aspect of the immune system, namely, the
distribution of recirculating lymphocytes in various
organs throughout the body. This distribution gains
importance because: i) it...