Rapamycin (Rapa) and dietary restriction (DR) have consistently
been shown to increase lifespan. To investigate whether Rapa
and DR affect similar pathways in mice, we compared the effects
of feeding mice ad libitum (AL), Rapa, DR, or a combination of
Rapa and DR (Rapa + DR) on the transcriptome and...
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Rapa and DR; no metabolites in Rapa-treated mice were
changed significantly from AL mice, whereas 173
It is well known that in mice the extension in lifespan by rapamycin is sexually dimorphic, in that it has a larger effect in females than males. In a previous study we showed that in male C57BL6 mice, rapamycin had less profound effects in both gene expression and liver metabolites...
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compared to dietary restriction (DR), but no
data was available in females. Because recent studies showed
The peptidyl nucleoside blasticidin S (BS) isolated from Streptomyces griseochromogenes was the first non-mercurial fungicide used on a large scale to prevent rice blast. In the biosynthesis of BS, leucylblasticidin S (LBS) was suggested as the penultimate metabolite with 20-fold less inhibitory activity than the final product BS. Incomplete conversion...
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RNA samples were treated with DNase
(Fermentas) for 4 h at 37 °C. No DNA contamination was verified
The peptidyl nucleoside blasticidin S (BS) isolated from Streptomyces griseochromogenes was the first non-mercurial fungicide used on a large scale to prevent rice blast. In the biosynthesis of BS, leucylblasticidin S (LBS) was suggested as the penultimate metabolite with 20-fold less inhibitory activity than the final product BS. Incomplete conversion...
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antibiotic maturation and the first report of
hydrolysis of beta amide linkage by this conserved enzyme
Forests play a critical role sequestering atmospheric carbon dioxide, partially offsetting greenhouse gas emissions, and thereby mitigating climate change. Forest management, natural disturbances, and the fate of carbon in wood products strongly influence carbon sequestration and emissions in the forest sector. Government policies, carbon offset and trading programs, and sustainable...
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evaluation was
beyond the scope of this review. From the
three general groups above, 41 yes/no ques-
tions
Forests play a critical role sequestering atmospheric carbon dioxide, partially offsetting greenhouse gas emissions, and thereby mitigating climate change. Forest management, natural disturbances, and the fate of carbon in wood products strongly influence carbon sequestration and emissions in the forest sector. Government policies, carbon offset and trading programs, and sustainable...
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Change and Forestry (2003) report. Tier I IPCC 2006 refers
to Tier I methods outlined in the IPCC
This study investigated how lidar-derived vegetation indices, disturbance history from Landsat time series (LTS)
imagery, plot location accuracy, and plot size influenced accuracy of statistical spatial models (nearest-neighbor
imputation maps) of forest vegetation composition and structure. Nearest-neighbor (NN) imputation maps were
developed for 539,000 ha in the central Oregon Cascades,...
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response variables from larger whole
plots. No single map had optimal results for every mapped variable
Zebra Chip (ZC) was confirmed in the Columbia Basin potato production area of Oregon and Washington in 2011. This is a serious disease first documented in Saltillo, Mexico in 1994. In 2000 the disease was identified in South Texas and since then, ZC has been reported in Arizona, California, Colorado,...
The zebrafish (Danio rerio) is emerging as a new important species for studying brain mechanisms and its deficits. Focusing on selected CNS disorders (brain cancer, epilepsy and anxiety) and using them as examples, we discuss the value of zebrafish models in translational neuroscience, and their contribution to neuroimaging, circuit-level and...
A recombinant inbred line (RIL) mapping population developed from a cross between winter wheat (Triticum aestivum L.)
cultivars Coda and Brundage was evaluated for reaction to stripe rust (caused by Puccinia striiformis f. sp. tritici). Two
hundred and sixty eight RIL from the population were evaluated in replicated field trials...
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USDA National Institute of Food and Agriculture. The funders had no role in study design, data