The furanyl diterpenoid family of natural products has drawn the attention of both synthetic organic chemists and pharmacologists due to their complex structural architectures and diverse biological activity. Among them, wortmannin has been most extensively studied for biological activities. All these furanyl diterpenoids consist of a highly strained naptha[1,8-bc]furan core,...
Software testing is of critical importance for the success of software projects. Current inefficient testing methods often still take up half or more of a software project's budget. Automatic test data generation is the most promising way to lower the software testing cost. Manually creating testing data is expensive and...
During heel-toe running, the vertical ground reaction force (VGRF) profile has both impact and active peaks. Although the mass-spring model (a single mass and a linear spring) is simple and useful to predict running characteristics, its simulation of VGRF profiles produces only a single peak rather than the double peak...
Domesticated forms of wheat exhibit traits that have increased their adaptation
to cultivation by humans. Some of the most critical adaptive differences involve
changes to morphological features that make the crop easier to harvest like ear rachis
stiffness (brittle to non-brittle rachis) and the ease with which the seed is...
Hybridization, polyploidy, and apomixis have made phylogenetic estimation in Rubus challenging. I used target capture to sequence approximately 1000 low copy nuclear loci and the chloroplast genome for 94 accessions representing the genus Rubus and distributed worldwide. Species phylogenies were estimated using two coalescent based methods, ASTRAL-II and SVDQuartets, and...
In the environment, it is the unbound fraction of chemical (Cfree) which is able to diffuse across environmental interfaces and biological membranes. It is therefore Cfree which drives many important biological-environmental processes including contaminant transport, bioaccumulation and toxicity. Passive sampling devices (PSDs) offer a simplified and more accurate approach for...
Volcán Miño (21°11'S) is located on the westernmost periphery of a longlived complex of stratovolcarioes and domes called the Aucanquilcha Complex. The Aucanquilcha Complex ranges in age from 11 Ma to 1-lolocene and lies along the main N-S trending axis of Quaternary volcanoes in the Andean Central Volcanic Zone (CVZ)....
The environmental health science community recognizes polycyclic aromatic hydrocarbons (PAHs) as a re-emerging class of environmental pollutants due to their persistence and prominence in mixtures of concern. Due to their widespread distribution in the environment, exposure to PAHs often occur as complex chemical mixtures. Exposures are linked to numerous adverse...