The opportunistic pathogen Pseudomonas aeruginosa possesses two LuxR-LuxI
type quorum-sensing systems that use diffusible acyl-homoserine lactone molecules to
autoinduce and coordinate expression of multiple virulence factors. We conducted a highthroughput
screen for mutants deficient in skim-milk proteolysis—a quorum-sensing
dependent phenotype—using a nonredundant transposon-insertion library representing
most nonessential genes in P....
A second-order nonlinear diffraction theory is developed for a
large diameter circular cylinder under the action of surface gravity
waves of finite amplitude in water of-finite depth. Boundary value
problems are derived by using a perturbation expansion and the
solutions for the diffracted waves are given in terms of Fredholm...
Understanding the mechanisms regulating mitochondrial respiratory function and adaptations to metabolic challenges, such as exercise and high dietary fat, is necessary to promote skeletal muscle health and attenuate metabolic disease. Autophagy is a constitutively active degradation pathway that promotes mitochondrial turnover and is suppressed by insulin and activated by exercise....
A free-air gravity anomaly map of the area between 10°-17°N and
90°-101°W shows distinctive positive and negative anomalies which
parallel the Tehuatepec Ridge. The positive anomaly approximately
overlies the topographic expression of the ridge. On the wide continental
shelf southeast of the Gulf of Tehuantepec a positive gravity
anomaly with...