Polymorphonuclear leukocytes (PMN) from patients with chronic granulomatous disease (CGD) fail to produce microbicidal concentrations of reactive oxygen species (ROS) due to mutations in NOX2. Patients with CGD suffer from severe, life-threatening infections and inflammatory complications. Granulibacter bethesdensis is an emerging Gram-negative pathogen in CGD that resists killing by PMN...
It is a golden age for animal movement studies and so an opportune time to assess priorities for future work. We assembled 40 experts to identify key questions in this field, focussing on marine megafauna, which include a broad range of birds, mammals, reptiles, and fish. Research on these taxa...
Community college and university faculty members changing their practice of teaching have reported benefits to participating in peer support within communities of practice that offer an online knowledge sharing space. The ability of such online knowledge sharing to provide opportunities for collaborative knowledge building has made fostering a viable online...
The distribution of mobile marine predators often reflects underlying dynamic ecological processes. The geographical focus of this PhD is the South Taranaki Bight (STB) of New Zealand, where wind-driven coastal upwelling generates productivity and prey to support a blue whale foraging ground. The STB is also New Zealand’s most industrial...
Pursuit of the triple bottom line of economic, community and ecological sustainability has increased the complexity of fishery management; fisheries assessments require new types of data and analysis to guide science-based policy in addition to traditional biological information and modeling. We introduce the Fishery Performance Indicators (FPIs), a broadly applicable...
Improvements in instrumentation for fluorometric kinetic
measurements and the application of a new intensified diode array (IDA)
rapid scanning system to low level transient fluorescence measurements
are reported. This instrumentation is applied to a new fluorometric
kinetic method for thiamine (TM).
Modifications to the existing fluorometric reation rate instrument
include...
Massive Open Online Courses (MOOCs) have generated considerable excitement and considerable skepticism since their recent inception (e.g., Kim, 2014; Perna et al., 2014). By fall 2015, approximately 35 million people had participated in 4200 courses offered by over 550 institutions (Shah, 2015). In addition to MOOCs’ potential for expanding access...
Human development researchers consider adolescence a rich time for interest development and identity exploration. A relatively new movement in the Free-Choice Learning (FCL) arena, the Maker movement, offers learners interest-driven, experiential, often collaborative, and process-oriented activities ranging from game design (computer-based and otherwise) and robotics, to sewing LEDs into clothing...