An enhancement of the therapeutic effect and/or a reduction in
the toxicity have been shown by a variety of antineoplastic compounds
when glucose is added to the treatment schedule. A possible explanation
for this involves a selective change in intracellular pH of the
tumor tissue initiating a greater uptake of...
Rats were given single i.p. injections of BCNU to
investigate changes in hepatic cytochrome P-450 content and
specific activity in male rats. Microsomal P-450 levels
were unchanged from 6 hours to 7 days after BCNU treatment
but by day 21 they had decreased 45%. Ethylmorphine N-demethylase
activity (nm product x...
BCNU caused severe cholestasis in rats after a single intraperitoneal injection. The cholestasis was characterized by a selective reduction of the bile salt independent bile flow to 11% of control. Decreased food or water consumption by the treated rats apparently did not contribute to cholestasis. Measurements of plasma Na⁺ and...
Spawning coho, chinook, and chum salmon are annually surveyed in coastal streams by Department of Fish and Wildlife personnel. Annual peak counts of spawning salmon provide data for computing an index of coastal escapement which is plotted each year to chart spawning salmon trends over a period of years. This...
Life-history organization of the cutthroat trout (Oncorhvnchus clarki) may be viewed at various levels, including species, subspecies, metapopulation, population, or individual. Each level varies in spatial scale and temporal persistence, and components at each level continually change with changes in environment. Cutthroat trout are widely distributed throughout the western USA,...
The widespread introduction of trout to naturally fishless mountain lakes in the western United States has been accompanied by little research. The ecological role of trout populations occurring in 91 lakes of the central Selway Bitterroot Wilderness, Idaho, was examined with respect to 1) the sampling variability of biological and...
Two tributaries of the south fork of the Burnt River, near Unity Oregon were studied
during the summers of 2000 and 2001 to determine water heating and cooling
patterns. Hourly temperature data were recorded for air, water, and soil parameters
at four elevations 150m apart on Barney and Stevens Creeks....
Invasive plant species are expanding and transforming vegetative communities across Oregon and throughout the United States. Over the past three decades remote sensing, geographic information system (GIS), and Global Positioning System (GPS) technologies have been integrated to detect and map the distribution of noxious rangeland plants. This study developed low-cost...
The Boleyn home located in Portland Oregon (latitude 45°) is evaluated based on monitoring data taken from 1977 to 1982. The Boleyn home is a two-story (plus basement) frame home. It takes benefit of passive solar gains and is equipped with an active solar system. The active solar system consists...