Atherosclerosis is the underlying cause of ischemic heart disease and stroke and is the leading cause of death worldwide, especially in developed countries. As an inflammatory disease of arteries in a hyperlipidemic milieu, expression of adhesion molecules, such as endothelial-leukocyte adhesion molecule-1 (E-selectin) and intercellular adhesion molecule-1 (ICAM-1), on endothelial...
Top-performing approaches to embodied AI tasks like point-goal navigation often rely on training agents via reinforcement learning over tens of millions (or even billions) of experiential steps – learning neural agents that map directly from visual observations to actions. In this work, we question whether these extreme training durations are...
Improvement of manufacturing productivity is dependent on the successful
automation of manufacturing processes, the success of which is based in turn upon
the availability of information which describes the state of manufacturing operations.
Acoustic Emission (AE) signals related to the cutting process and tool wear have
been recently applied to...
Hepatitis E virus (HEV) infection is a cause of hepatitis in humans worldwide. Recently, persistent and chronic HEV infections have been recognized as a serious clinical problem, especially in immunocompromised individuals. To date, there are no FDA-approved HEV-specific antiviral drugs. In this study, we designed and evaluated antisense peptide-conjugated morpholino...
A study was conducted to evaluate the developmental toxicity of three commonly detected mycotoxins in food (deoxynivalenol, patulin, and zearalenone) using the zebrafish (Danio rerio) model. Mycotoxin exposures were carried out at five concentrations (0.0064, 0.064, 0.64, 6.4, and 64 μM). Morphological and photomotor screenings were conducted at 24 hours...
A novel table-top, microreactor-assisted nanomaterial deposition (MAND™) process, which combines the merits of microreaction technology with solution-phase nanomaterial synthesis and film deposition, was used to grow a nanostructured ZnO anti-reflective coating on a textured silicon substrate from aqueous solution. The subwavelength, anti-reflective nanostructures mimicked the structure and performance of the...
This study investigated the effects of visual cues, muscular fatigue, task performance and experience of working on inclined
surfaces on activity of postural muscles in the lower limbs associated with maintaining balance on three inclined surfaces –
08, 148 and 268. Normalised electromyographic (NEMG) data were collected in 44 professional...
Background: The identification of the loci and specific alleles underlying variation in quantitative traits is an important goal for evolutionary biologists and breeders. Despite major advancements in genomics technology, moving from QTL to causal alleles remains a major challenge in genetics research. Near-isogenic lines are the ideal raw material for...