Here we report a new transgenic expression system by combination of liver-specific expression, mifepristone induction and Cre-loxP recombination to conditionally control the expression of oncogenic kras[superscript]V12. This transgenic system allowed expression of kras[superscript]V12 specifically in the liver by a brief exposure of mifepristone to induce permanent genomic recombination mediated by...
Here we report a new transgenic expression system by combination of liver-specific expression,
mifepristone induction and Cre-loxP recombination to conditionally control the expression of oncogenic
kras[superscript]V12. This transgenic system allowed expression of kras[superscript]V12 specifically in the liver by a brief exposure
of mifepristone to induce permanent genomic recombination mediated by...
Full Text:
expression in transgenic zebrafish
Anh Tuan Nguyen
1, 2
, Vivien Koh
1
, Jan M. Spitsbergen
2
Here we report a new transgenic expression system by combination of liver-specific expression,
mifepristone induction and Cre-loxP recombination to conditionally control the expression of oncogenic
kras[superscript]V12. This transgenic system allowed expression of kras[superscript]V12 specifically in the liver by a brief exposure
of mifepristone to induce permanent genomic recombination mediated by...
Full Text:
Anh Tuan Nguyen
Vivien Koh
Jan M. Spitsbergen
Zhiyuan
Hepatocellular carcinoma (HCC) is currently one of the top lethal cancers with an increasing
trend. Deregulation of MYC in HCC is frequently detected and always correlated with poor
prognosis. As the zebrafish genome contains two differentially expressed zebrafish myc
orthologs, myca and mycb, it remains unclear about the oncogenicity of...
Full Text:
Mutation
Sun, L., Nguyen, A. T., Spitsbergen, J. M., & Gong, Z. (2015). Myc-Induced Liver
Tumors in
Hepatocellular carcinoma (HCC) is currently one of the top lethal cancers with an increasing
trend. Deregulation of MYC in HCC is frequently detected and always correlated with poor
prognosis. As the zebrafish genome contains two differentially expressed zebrafish myc
orthologs, myca and mycb, it remains unclear about the oncogenicity of...
Hepatocellular carcinoma (HCC) is currently one of the top lethal cancers with an increasing trend. Deregulation of MYC in HCC is frequently detected and always correlated with poor prognosis. As the zebrafish genome contains two differentially expressed zebrafish myc orthologs, myca and mycb, it remains unclear about the oncogenicity of...
The paper adopts the double-bootstrap data envelopment analysis developed by Simar and Wilson in 2007 to estimate and explain technical efficiency of white-leg shrimp farming in Ninh Thuan, Vietnam. This procedure not only enables consistent inference within models explaining efficiency scores but also produces confidence intervals for these efficiency scores....
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, Nha Trang University, Vietnam, thaplv@ntu.edu.vn, thapdhts@yahoo.com
LE, KIM LONG
The Faculty
Soil nitrogen exists largely as organic matter, including plant liter, dead animal matter, and microbial necromass. About 90% of soil organic nitrogen is proteinaceous material that is too large for plants and microorganisms to assimilate directly. Protein depolymerization therefore plays a critical role in mobilizing this organic source of nitrogen,...
Until a few years ago, wireless-capable laptops were considered novelties by many. It is now hard to find a laptop or a hand-held computing device that is not wireless-ready. As wireless devices are becoming commodities, they have also become an indispensable part of the modern society. Not surprisingly, research in...
The proportion of professional staff on higher education campuses has significantly grown in recent decades. Despite this growth, the racial makeup of this employee population still does not reflect the increasing diversity of students in higher education. While higher education institutions pronounce their commitments to developing diversity, equity, and inclusion...